Merina Varghese
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Explore the profile of Merina Varghese including associated specialties, affiliations and a list of published articles.
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49
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1595
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Recent Articles
1.
Castranio E, Varghese M, Argyrousi E, Tripathi K, Soderberg L, Bresnahan E, et al.
bioRxiv
. 2025 Mar;
PMID: 40060689
Teaser: APP "NFA-Aβ only" mice reveal clinically relevant mechanisms despite the absence of detectable inflammation.
2.
Chakravarty S, Varghese M, Fan S, Taylor R, Chakravarti R, Chattopadhyay S
Sci Adv
. 2024 Aug;
10(32):eadn2858.
PMID: 39121222
Viral inflammation contributes to pathogenesis and mortality during respiratory virus infections. IRF3, a critical component of innate antiviral immune responses, interacts with pro-inflammatory transcription factor NF-κB, and inhibits its activity....
3.
Castro-Mendoza P, Weaver C, Chang W, Medalla M, Rockland K, Lowery L, et al.
Brain Struct Funct
. 2024 Jun;
229(7):1495-1525.
PMID: 38943018
In this novel large-scale multiplexed immunofluorescence study we comprehensively characterized and compared layer-specific proteomic features within regions of interest of the widely divergent dorsolateral prefrontal cortex (A46) and primary visual...
4.
Ferreira A, Hemmer B, Philippi S, Grau-Perales A, Rosenstadt J, Liu H, et al.
Mol Psychiatry
. 2023 Nov;
28(9):3943-3954.
PMID: 37914840
Functional output of the hippocampus, a brain region subserving memory function, depends on highly orchestrated cellular and molecular processes that regulate synaptic plasticity throughout life. The structural requirements of such...
5.
Costantini I, Morgan L, Yang J, Balbastre Y, Varadarajan D, Pesce L, et al.
Sci Adv
. 2023 Oct;
9(41):eadg3844.
PMID: 37824623
Brain cells are arranged in laminar, nuclear, or columnar structures, spanning a range of scales. Here, we construct a reliable cell census in the frontal lobe of human cerebral cortex...
6.
Eyford B, Lazarczyk M, Choi K, Varghese M, Arora H, Kari S, et al.
Sci Rep
. 2023 Aug;
13(1):13079.
PMID: 37567897
The interplay between AMPA-type glutamate receptors (AMPARs) and major histocompatibility complex class I (MHC-I) proteins in regulating synaptic signaling is a crucial aspect of central nervous system (CNS) function. In...
7.
Hawrylycz M, Martone M, Ascoli G, Bjaalie J, Dong H, Ghosh S, et al.
PLoS Biol
. 2023 Jun;
21(6):e3002133.
PMID: 37390046
Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is...
8.
Gama Sosa M, De Gasperi R, Pryor D, Perez Garcia G, Perez G, Abutarboush R, et al.
Acta Neuropathol Commun
. 2023 May;
11(1):81.
PMID: 37173747
In the course of military operations in modern war theaters, blast exposures are associated with the development of a variety of mental health disorders associated with a post-traumatic stress disorder-related...
9.
Lazarczyk M, Eyford B, Varghese M, Arora H, Munro L, Warda T, et al.
Sci Rep
. 2023 Apr;
13(1):6448.
PMID: 37081001
Major histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown. Here we...
10.
Sharma D, Cheng B, Jaiswal M, Zhang X, Kumar A, Parikh N, et al.
Cereb Cortex
. 2023 Jan;
33(10):6449-6464.
PMID: 36646459
Prematurely born infants are deprived of maternal hormones and cared for in the stressful environment of Neonatal Intensive Care Units (NICUs). They suffer from long-lasting deficits in learning and memory....