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Danielle Tenen

Explore the profile of Danielle Tenen including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1573
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Recent Articles
1.
Gulko A, Essene A, Belmont-Rausch D, Veregge M, Pant D, Tenen D, et al.
STAR Protoc . 2024 Feb; 5(1):102893. PMID: 38416649
Adipocyte size and fragility and commercial kit costs impose significant limitations on single-cell RNA sequencing of adipose tissue. Accordingly, we developed a workflow to isolate and sample-barcode nuclei from individual...
2.
Emont M, Jacobs C, Essene A, Pant D, Tenen D, Colleluori G, et al.
Nature . 2023 Jul; 620(7973):E14. PMID: 37495702
No abstract available.
3.
Emont M, Jacobs C, Essene A, Pant D, Tenen D, Colleluori G, et al.
Nature . 2022 Mar; 603(7903):926-933. PMID: 35296864
White adipose tissue, once regarded as morphologically and functionally bland, is now recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of biological processes including...
4.
Li J, Li E, Czepielewski R, Chi J, Guo X, Han Y, et al.
Cell Metab . 2021 May; 33(7):1449-1465.e6. PMID: 34038712
The lymphatic vasculature plays important roles in the physiology of the organs in which it resides, though a clear mechanistic understanding of how this crosstalk is mediated is lacking. Here,...
5.
Roh H, Kumari M, Taleb S, Tenen D, Jacobs C, Lyubetskaya A, et al.
Mol Metab . 2020 Sep; 42:101086. PMID: 32992037
Objective: Obesity due to overnutrition causes adipose tissue dysfunction, which is a critical pathological step on the road to type 2 diabetes (T2D) and other metabolic disorders. In this study,...
6.
Hall J, Ramachandran D, Roh H, DiSpirito J, Belchior T, Zushin P, et al.
Cell Metab . 2020 Sep; 32(4):665-675.e6. PMID: 32941798
The thiazolidinediones (TZDs) are ligands of PPARγ that improve insulin sensitivity, but their use is limited by significant side effects. Recently, we demonstrated a mechanism wherein TZDs improve insulin sensitivity...
7.
Kazak L, Rahbani J, Samborska B, Lu G, Jedrychowski M, Lajoie M, et al.
Nat Metab . 2019 Jun; 1(3):360-370. PMID: 31161155
No abstract available.
8.
Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, et al.
Cell Metab . 2018 Aug; 28(4):631-643.e3. PMID: 30078553
Skeletal muscle and brown adipose tissue (BAT) are functionally linked, as exercise increases browning via secretion of myokines. It is unknown whether BAT affects muscle function. Here, we find that...
9.
Roh H, Tsai L, Shao M, Tenen D, Shen Y, Kumari M, et al.
Cell Metab . 2018 Apr; 27(5):1121-1137.e5. PMID: 29657031
Beige and brown adipocytes generate heat in response to reductions in ambient temperature. When warmed, both beige and brown adipocytes exhibit morphological "whitening," but it is unknown whether or to...
10.
Campbell J, Macosko E, Fenselau H, Pers T, Lyubetskaya A, Tenen D, et al.
Nat Neurosci . 2017 Feb; 20(3):484-496. PMID: 28166221
The hypothalamic arcuate-median eminence complex (Arc-ME) controls energy balance, fertility and growth through molecularly distinct cell types, many of which remain unknown. To catalog cell types in an unbiased way,...