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Danielle Tenen

Explore the profile of Danielle Tenen including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1573
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Recent Articles
11.
Roh H, Tsai L, Lyubetskaya A, Tenen D, Kumari M, Rosen E
Cell Rep . 2017 Jan; 18(4):1048-1061. PMID: 28122230
Epigenomic mechanisms direct distinct gene expression programs for different cell types. Various in vivo tissues have been subjected to epigenomic analysis; however, these studies have been limited by cellular heterogeneity,...
12.
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, et al.
J Clin Invest . 2016 Jul; 126(8):2839-54. PMID: 27400129
The chronic inflammatory state that accompanies obesity is a major contributor to insulin resistance and other dysfunctional adaptations in adipose tissue. Cellular and secreted factors promote the inflammatory milieu of...
13.
Hendrickson D, Kelley D, Tenen D, Bernstein B, Rinn J
Genome Biol . 2016 Feb; 17:28. PMID: 26883116
Background: Recent evidence suggests that RNA interaction can regulate the activity and localization of chromatin-associated proteins. However, it is unknown if these observations are specialized instances for a few key...
14.
Cheloufi S, Elling U, Hopfgartner B, Jung Y, Murn J, Ninova M, et al.
Nature . 2015 Dec; 528(7581):218-24. PMID: 26659182
Cellular differentiation involves profound remodelling of chromatic landscapes, yet the mechanisms by which somatic cell identity is subsequently maintained remain incompletely understood. To further elucidate regulatory pathways that safeguard the...
15.
Kelley D, Hendrickson D, Tenen D, Rinn J
Genome Biol . 2015 Jan; 15(12):537. PMID: 25572935
Background: Transposable elements (TEs) have significantly influenced the evolution of transcriptional regulatory networks in the human genome. Post-transcriptional regulation of human genes by TE-derived sequences has been observed in specific...