Linus T Tsai
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Explore the profile of Linus T Tsai including associated specialties, affiliations and a list of published articles.
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13
Citations
826
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Recent Articles
1.
Westcott G, Emont M, Gulko A, Zhou Z, Kim C, Varma G, et al.
bioRxiv
. 2025 Mar;
PMID: 40027673
Chronic lymphedema is a progressive, disfiguring disease that results from dysfunction of the lymphatic vasculature, causing distal accumulation of interstitial fluid, localized development of tissue edema, and expansion of subcutaneous...
2.
Vargas-Castillo A, Sun Y, Smythers A, Grauvogel L, Dumesic P, Emont M, et al.
Cell Metab
. 2024 Jul;
36(9):2146-2155.e5.
PMID: 39084217
Although uncoupling protein 1 (UCP1) is established as a major contributor to adipose thermogenesis, recent data have illustrated an important role for alternative pathways, particularly the futile creatine cycle (FCC)....
3.
Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, et al.
Nat Commun
. 2024 Mar;
15(1):1966.
PMID: 38438345
The "dorsal pons", or "dorsal pontine tegmentum" (dPnTg), is part of the brainstem. It is a complex, densely packed region whose nuclei are involved in regulating many vital functions. Notable...
4.
Gulko A, Essene A, Belmont-Rausch D, Veregge M, Pant D, Tenen D, et al.
STAR Protoc
. 2024 Feb;
5(1):102893.
PMID: 38416649
Adipocyte size and fragility and commercial kit costs impose significant limitations on single-cell RNA sequencing of adipose tissue. Accordingly, we developed a workflow to isolate and sample-barcode nuclei from individual...
5.
Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, et al.
bioRxiv
. 2023 Nov;
PMID: 38014113
The "dorsal pons", or "dorsal pontine tegmentum" (dPnTg), is part of the brainstem. It is a complex, densely packed region whose nuclei are involved in regulating many vital functions. Notable...
6.
Emont M, Jacobs C, Essene A, Pant D, Tenen D, Colleluori G, et al.
Nature
. 2023 Jul;
620(7973):E14.
PMID: 37495702
No abstract available.
7.
Rajcsanyi L, Hoffmann A, Ghosh A, Matrisch-Dinkler B, Zheng Y, Peters T, et al.
Front Genet
. 2023 Apr;
14:1128133.
PMID: 37101650
Increased thermogenesis in brown adipose tissue might have an obesity-reducing effect in humans. In transgenic mice, depletion of genes involved in creatine metabolism results in disrupted thermogenic capacity and altered...
8.
Sargsyan A, Doridot L, Hannou S, Tong W, Srinivasan H, Ivison R, et al.
JCI Insight
. 2022 Nov;
8(1).
PMID: 36413406
Carbohydrate response element-binding protein (ChREBP) is a carbohydrate-sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus...
9.
Xiao H, Bozi L, Sun Y, Riley C, Philip V, Chen M, et al.
Cell
. 2022 Nov;
185(24):4654-4673.e28.
PMID: 36334589
Brown adipose tissue (BAT) regulates metabolic physiology. However, nearly all mechanistic studies of BAT protein function occur in a single inbred mouse strain, which has limited the understanding of generalizable...
10.
Emont M, Jacobs C, Essene A, Pant D, Tenen D, Colleluori G, et al.
Nature
. 2022 Mar;
603(7903):926-933.
PMID: 35296864
White adipose tissue, once regarded as morphologically and functionally bland, is now recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of biological processes including...