Danielle L Widner
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Explore the profile of Danielle L Widner including associated specialties, affiliations and a list of published articles.
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5
Citations
23
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Recent Articles
1.
Polaske T, West K, Zhao K, Widner D, York J, Blackwell H
Isr J Chem
. 2024 May;
63(5-6).
PMID: 38765792
is a ubiquitous bacterium that has become a major threat to human health due to its extensive toxin production and tremendous capacity for antibiotic resistance (e.g., MRSA "superbug" infections). Amid...
2.
Sherlock M, Higgs G, Yu D, Widner D, White N, Sudarsan N, et al.
RNA Biol
. 2022 Sep;
19(1):1059-1076.
PMID: 36093908
Riboswitch architectures that involve the binding of a single ligand to a single RNA aptamer domain result in ordinary dose-response curves that require approximately a 100-fold change in ligand concentration...
3.
Yang Y, Harris K, Widner D, Breaker R
Proc Natl Acad Sci U S A
. 2021 Feb;
118(9).
PMID: 33619097
The OLE (ornate, large, and extremophilic) RNA class is one of the most complex and well-conserved bacterial noncoding RNAs known to exist. This RNA is known to be important for...
4.
Widner D, Harris K, Corey L, Breaker R
J Biol Chem
. 2020 May;
295(28):9326-9334.
PMID: 32376692
Noncoding RNAs (ncRNAs) longer than 200 nucleotides are rare in bacteria, likely because bacterial genomes are under strong evolutionary pressures to maintain a small genome size. Of the long ncRNAs...
5.
Widner D, Knauf Q, Merucci M, Fritz T, Sauer J, Speetzen E, et al.
J Org Chem
. 2014 Jun;
79(13):6269-78.
PMID: 24931463
Intramolecular halogen bonds between aryl halide donors and suitable acceptors, such as carbonyl or quinolinyl groups, held in proximity by 1,2-aryldiyne linkers, provide triangular structures in the solid state. Aryldiyne...