Daniel R Wahl
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Explore the profile of Daniel R Wahl including associated specialties, affiliations and a list of published articles.
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68
Citations
1996
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Recent Articles
11.
Scott A, Mittal A, Meghdadi B, Palavalasa S, Achreja A, OBrien A, et al.
medRxiv
. 2023 Nov;
PMID: 37961582
Significance: This study is the first to directly measure biosynthetic flux in both glioma and cortical tissue in human brain cancer patients. Brain tumors rewire glucose carbon utilization away from...
12.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Wilder-Romans K, et al.
Cancer Discov
. 2023 Oct;
14(1):158-175.
PMID: 37902550
Significance: A newly described GTP-dependent signaling axis is an unexpected link between nucleotide metabolism and DNA repair. Disrupting this pathway can overcome cancer resistance to genotoxic therapy while augmenting it...
13.
Peterson E, Sajjakulnukit P, Scott A, Heaslip C, Andren A, Wilder-Romans K, et al.
Res Sq
. 2023 Oct;
PMID: 37790517
Background: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine...
14.
Umemura Y, Orringer D, Junck L, Varela M, West M, Faisal S, et al.
Lancet Oncol
. 2023 Sep;
24(9):1042-1052.
PMID: 37657463
Background: High-grade gliomas have a poor prognosis and do not respond well to treatment. Effective cancer immune responses depend on functional immune cells, which are typically absent from the brain....
15.
Bailleul J, Ruan Y, Abdulrahman L, Scott A, Yazal T, Sung D, et al.
Neuro Oncol
. 2023 Jun;
25(11):1989-2000.
PMID: 37279645
Background: Resistance to existing therapies is a significant challenge in improving outcomes for glioblastoma (GBM) patients. Metabolic plasticity has emerged as an important contributor to therapy resistance, including radiation therapy...
16.
Apiz Saab J, Dzierozynski L, Jonker P, AminiTabrizi R, Shah H, Menjivar R, et al.
Elife
. 2023 May;
12.
PMID: 37254839
Nutrient stress in the tumor microenvironment requires cancer cells to adopt adaptive metabolic programs for survival and proliferation. Therefore, knowledge of microenvironmental nutrient levels and how cancer cells cope with...
17.
Watson D, Bayik D, Storevik S, Moreino S, Sprowls S, Han J, et al.
Nat Cancer
. 2023 May;
4(5):648-664.
PMID: 37169842
The transfer of intact mitochondria between heterogeneous cell types has been confirmed in various settings, including cancer. However, the functional implications of mitochondria transfer on tumor biology are poorly understood....
18.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Kari W, et al.
bioRxiv
. 2023 Apr;
PMID: 37090571
How cell metabolism regulates DNA repair is incompletely understood. Here, we define a GTP-mediated signaling cascade that links metabolism to DNA repair and has significant therapeutic implications. GTP, but not...
19.
Scott A, Correa L, Edwards D, Sun Y, Ravikumar V, Andren A, et al.
Antioxid Redox Signal
. 2023 Feb;
39(13-15):942-956.
PMID: 36852494
Targeting tumor metabolism may improve the outcomes for patients with glioblastoma (GBM). To further preclinical efforts targeting metabolism in GBM, we tested the hypothesis that brain tumors can be stratified...
20.
Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma
Parsels L, Wahl D, Koschmann C, Morgan M, Zhang Q
Neoplasia
. 2023 Feb;
37:100881.
PMID: 36724689
Diffuse intrinsic pontine glioma (DIPG) is a rare but highly lethal pediatric and adolescent tumor located in the pons of the brainstem. DIPGs harbor unique and specific pathological and molecular...