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Meredith A Morgan

Explore the profile of Meredith A Morgan including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 3647
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Recent Articles
1.
Valvo V, Zhang Q, Jiang L, Holcomb E, Pearson A, Edmunds A, et al.
Mol Cancer Ther . 2024 Dec; :OF1-OF16. PMID: 39688341
PARP inhibitors sensitize pancreatic ductal adenocarcinoma (PDAC) to radiation by inducing DNA damage and replication stress. These mechanisms also have the potential to enhance radiation-induced type I interferon (T1IFN)-mediated antitumoral...
2.
Korimerla N, Meghdadi B, Haq I, Wilder-Romans K, Xu J, Becker N, et al.
bioRxiv . 2024 Dec; PMID: 39651281
Glioblastoma (GBM) is uniformly lethal due to profound treatment resistance. Altered cellular metabolism is a key mediator of GBM treatment resistance. Uptake of the essential sulfur-containing amino acid methionine is...
3.
Elaimy A, El-Derany M, James J, Wang Z, Pearson A, Holcomb E, et al.
JCI Insight . 2024 Sep; 9(21). PMID: 39287988
End-stage liver disease is marked by portal hypertension, systemic elevations in ammonia, and development of hepatocellular carcinoma (HCC). While these clinical consequences of cirrhosis are well described, it remains poorly...
4.
Guo Y, Li Z, Parsels L, Wang Z, Parsels J, Dalvi A, et al.
bioRxiv . 2024 Sep; PMID: 39253432
Background: Radiotherapy (RT) is the primary treatment for diffuse midline glioma (DMG), a lethal pediatric malignancy defined by histone H3 lysine 27-to-methionine (H3K27M) mutation. Based on the loss of H3K27...
5.
Valvo V, Vitale E, Tigano M, Evans R, Morgan M, Zhang Q
Front Oncol . 2024 Jun; 14:1424895. PMID: 38939331
[This corrects the article DOI: 10.3389/fonc.2023.1257622.].
6.
Peterson E, Sajjakulnukit P, Scott A, Heaslip C, Andren A, Wilder-Romans K, et al.
Cancer Metab . 2024 Apr; 12(1):11. PMID: 38594734
Background: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine...
7.
Zhang Q, Jiang L, Wang W, Huber A, Valvo V, Jungles K, et al.
JCI Insight . 2024 Feb; 9(6). PMID: 38376927
Radiotherapy induces a type I interferon-mediated (T1IFN-mediated) antitumoral immune response that we hypothesized could be potentiated by a first-in-class ataxia telangiectasia mutated (ATM) inhibitor, leading to enhanced innate immune signaling,...
8.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Wilder-Romans K, et al.
Cancer Discov . 2023 Oct; 14(1):158-175. PMID: 37902550
Significance: A newly described GTP-dependent signaling axis is an unexpected link between nucleotide metabolism and DNA repair. Disrupting this pathway can overcome cancer resistance to genotoxic therapy while augmenting it...
9.
Peterson E, Sajjakulnukit P, Scott A, Heaslip C, Andren A, Wilder-Romans K, et al.
Res Sq . 2023 Oct; PMID: 37790517
Background: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine...
10.
Valvo V, Vitale E, Tigano M, Evans R, Morgan M, Zhang Q
Front Oncol . 2023 Aug; 13:1257622. PMID: 37560464
No abstract available.