Andrew J Scott
Overview
Explore the profile of Andrew J Scott including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
382
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Recent Articles
1.
Korimerla N, Meghdadi B, Haq I, Wilder-Romans K, Xu J, Becker N, et al.
bioRxiv
. 2024 Dec;
PMID: 39651281
Glioblastoma (GBM) is uniformly lethal due to profound treatment resistance. Altered cellular metabolism is a key mediator of GBM treatment resistance. Uptake of the essential sulfur-containing amino acid methionine is...
2.
Morris R, Chappell H, Scott A, Borissova A, Smith J
Cryst Growth Des
. 2024 Oct;
24(19):8063-8075.
PMID: 39372599
We use modeling (CASTEP) to help elucidate the crystallization phenomena and chemistry behind kidney stone composition and formation. To explore the stone formation process, we have constructed a surface model...
3.
Sharma G, Loganathan S, Barimah E, Georgopoulou P, Taylor E, Scott A, et al.
Chemphyschem
. 2024 Jun;
25(19):e202400109.
PMID: 38887191
The paper describes an investigation of phase decomposition of apatite lattice doped with rare earth ions (cerium, samarium, and holmium) at temperatures ranging from 25-1200 °C. The rare-earth ion-doped apatite...
4.
Peterson E, Sajjakulnukit P, Scott A, Heaslip C, Andren A, Wilder-Romans K, et al.
Cancer Metab
. 2024 Apr;
12(1):11.
PMID: 38594734
Background: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine...
5.
Middleton J, Ghadiri M, Scott A
Pharmaceutics
. 2024 Mar;
16(3).
PMID: 38543327
Triboelectrification is a ubiquitous and poorly understood phenomenon in powder processing, particularly for pharmaceutical powders. Charged particles can adhere to vessel walls, causing sheeting; they can also cause agglomeration, threatening...
6.
Hills O, Noble I, Heyam A, Scott A, Smith J, Chappell H
Microbiology (Reading)
. 2023 Dec;
169(12).
PMID: 38117289
Intravenous gallium nitrate therapy is a novel therapeutic strategy deployed to combat chronic biofilm infections in the lungs of cystic fibrosis (CF) patients by interfering with iron (Fe) uptake. The...
7.
Scott A, Mittal A, Meghdadi B, Palavalasa S, Achreja A, OBrien A, et al.
medRxiv
. 2023 Nov;
PMID: 37961582
Significance: This study is the first to directly measure biosynthetic flux in both glioma and cortical tissue in human brain cancer patients. Brain tumors rewire glucose carbon utilization away from...
8.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Wilder-Romans K, et al.
Cancer Discov
. 2023 Oct;
14(1):158-175.
PMID: 37902550
Significance: A newly described GTP-dependent signaling axis is an unexpected link between nucleotide metabolism and DNA repair. Disrupting this pathway can overcome cancer resistance to genotoxic therapy while augmenting it...
9.
Peterson E, Sajjakulnukit P, Scott A, Heaslip C, Andren A, Wilder-Romans K, et al.
Res Sq
. 2023 Oct;
PMID: 37790517
Background: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine...
10.
Middleton J, Scott A, Storey R, Marucci M, Ghadiri M
Cryst Growth Des
. 2023 Sep;
23(9):6308-6317.
PMID: 37692333
Crystals of active pharmaceutical ingredients (API) are prone to triboelectric charging due to their dielectric nature. This characteristic, coupled with their typically low density and often large aspect ratio, poses...