Daniel R Crooks
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Explore the profile of Daniel R Crooks including associated specialties, affiliations and a list of published articles.
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41
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1242
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Recent Articles
1.
Hsueh J, Mendhiratta N, Solomon J, Miller M, Ryan B, Ricketts C, et al.
Urol Oncol
. 2025 Feb;
PMID: 40011184
Purpose: Hereditary pheochromocytomas and paragangliomas can be associated with mutations in the mitochondrial enzyme succinate dehydrogenase. Due to their heterogenous clinical presentation, no clear universal screening guidelines are currently available....
2.
Kishimoto S, Horie K, Devasahayam N, Yamashita K, Gadisetti C, Yamamoto K, et al.
bioRxiv
. 2025 Feb;
PMID: 39896573
Renal oxygenation is essential for maintaining kidney function. Disruptions in oxygen delivery can lead to renal hypoxia, which can exacerbate kidney injury through multiple pathways, including inflammation, oxidative stress, and...
3.
Arner E, Jennings E, Crooks D, Ricketts C, Wolf M, Cottam M, et al.
bioRxiv
. 2025 Jan;
PMID: 39829901
Metastasis causes most cancer deaths and reflects transitions from primary tumor escape to seeding and growth at metastatic sites. Epithelial-to-mesenchymal transition (EMT) is important early in metastasis to enable cancer...
4.
Najera S, Ricketts C, Schmidt L, Medina J, Saito K, Ileva L, et al.
Mol Cancer Ther
. 2024 Oct;
24(2):200-213.
PMID: 39397296
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an inherited cancer syndrome caused by germline pathogenic variants in the fumarate hydratase (FH) gene. Affected individuals are at risk for developing...
5.
Webster B, Ricketts C, Vocke C, Gamble D, Crooks D, Yang Y, et al.
JCO Precis Oncol
. 2024 Jul;
8:e2400188.
PMID: 39038244
Comprehensive molecular characterization and effective therapy in a rare case of metastatic renal oncocytoma.
6.
Kishimoto S, Crooks D, Yasunori O, Kota Y, Yamamoto K, Linehan W, et al.
Free Radic Biol Med
. 2024 Jul;
222:579-587.
PMID: 38992394
Hypoxic tumor microenvironments pose a significant challenge in cancer treatment. Hypoxia-activated prodrugs like evofosfamide aim to specifically target and eliminate these resistant cells. However, their effectiveness is often limited by...
7.
Fitzsimmons C, Mandler M, Lunger J, Chan D, Maligireddy S, Schmiechen A, et al.
NAR Cancer
. 2024 Feb;
6(1):zcae004.
PMID: 38328795
Metabolic reprogramming is a hallmark of cancer that facilitates changes in many adaptive biological processes. Mutations in the tricarboxylic acid cycle enzyme fumarate hydratase (FH) lead to fumarate accumulation and...
8.
Crooks D, Cawthon G, Fitzsimmons C, Perez M, Ricketts C, Vocke C, et al.
Hum Mol Genet
. 2023 Aug;
32(22):3135-3145.
PMID: 37561409
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant condition characterized by the development of cutaneous and uterine leiomyomas and risk for development of an aggressive form of...
9.
Schmidt L, Vocke C, Ricketts C, Blake Z, Choo K, Nielsen D, et al.
Urology
. 2023 Jun;
179:58-70.
PMID: 37331486
Objective: To characterize the clinical manifestations and genetic basis of a familial cancer syndrome in patients with lipomas and Birt-Hogg-Dubé-like clinical manifestations including fibrofolliculomas and trichodiscomas and kidney cancer. Methods:...
10.
Lang M, Schmidt L, Wilson K, Ricketts C, Sourbier C, Vocke C, et al.
J Exp Clin Cancer Res
. 2023 Apr;
42(1):99.
PMID: 37095531
Background: MiT-Renal Cell Carcinoma (RCC) is characterized by genomic translocations involving microphthalmia-associated transcription factor (MiT) family members TFE3, TFEB, or MITF. MiT-RCC represents a specific subtype of sporadic RCC that...