Christopher J Ricketts
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Explore the profile of Christopher J Ricketts including associated specialties, affiliations and a list of published articles.
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84
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4265
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Recent Articles
1.
Hsueh J, Mendhiratta N, Solomon J, Miller M, Ryan B, Ricketts C, et al.
Urol Oncol
. 2025 Feb;
PMID: 40011184
Purpose: Hereditary pheochromocytomas and paragangliomas can be associated with mutations in the mitochondrial enzyme succinate dehydrogenase. Due to their heterogenous clinical presentation, no clear universal screening guidelines are currently available....
2.
Fukushima H, Takao S, Furusawa A, Suzuki M, Yang Y, Ricketts C, et al.
Int J Cancer
. 2025 Feb;
PMID: 39936451
Carbonic anhydrase-9 (CA9) is highly expressed in clear cell renal cell carcinoma (ccRCC) cells despite no expression in normal kidney tissues. Thus, CA9 has been proposed as a theranostic target...
3.
Arner E, Jennings E, Crooks D, Ricketts C, Wolf M, Cottam M, et al.
bioRxiv
. 2025 Jan;
PMID: 39829901
Metastasis causes most cancer deaths and reflects transitions from primary tumor escape to seeding and growth at metastatic sites. Epithelial-to-mesenchymal transition (EMT) is important early in metastasis to enable cancer...
4.
Najera S, Ricketts C, Schmidt L, Medina J, Saito K, Ileva L, et al.
Mol Cancer Ther
. 2024 Oct;
24(2):200-213.
PMID: 39397296
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an inherited cancer syndrome caused by germline pathogenic variants in the fumarate hydratase (FH) gene. Affected individuals are at risk for developing...
5.
Stransky L, Gao W, Schmidt L, Bi K, Ricketts C, Ramesh V, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(41):e2408549121.
PMID: 39365820
CRISPR is revolutionizing the ability to do somatic gene editing in mice for the purpose of creating new cancer models. Inactivation of the tumor suppressor gene is the signature initiating...
6.
Vocke C, Ricketts C, Pack S, Raffeld M, Hewitt S, Lebensohn A, et al.
J Med Genet
. 2024 Sep;
61(11):1026-1030.
PMID: 39317422
von Hippel-Lindau (VHL) is an autosomal-dominant hereditary tumour susceptibility disease associated with pathogenic germline variants in the tumour suppressor gene. VHL patients are at increased risk of developing multiple benign...
7.
Wang L, Pattnaik A, Sahoo S, Stone E, Zhuang Y, Benton A, et al.
Nat Commun
. 2024 Aug;
15(1):7288.
PMID: 39179644
Correctly identifying perturbed biological pathways is a critical step in uncovering basic disease mechanisms and developing much-needed therapeutic strategies. However, whether current tools are optimal for unbiased discovery of relevant...
8.
Walter-Rodriguez B, Ricketts C, Linehan W, Merino M
Genes (Basel)
. 2024 Jul;
15(7).
PMID: 39062684
Introduction: Renal cell carcinoma is one of the ten more common malignant tumors worldwide, with a high incidence and mortality rate. Kidney cancer frequently presents at an advanced stage, and...
9.
Webster B, Ricketts C, Vocke C, Gamble D, Crooks D, Yang Y, et al.
JCO Precis Oncol
. 2024 Jul;
8:e2400188.
PMID: 39038244
Comprehensive molecular characterization and effective therapy in a rare case of metastatic renal oncocytoma.
10.
Li G, Chen L, Hsiao Y, Mannan R, Zhang Y, Luo J, et al.
Cell Rep Med
. 2024 May;
5(5):101547.
PMID: 38703764
Non-clear cell renal cell carcinomas (non-ccRCCs) encompass diverse malignant and benign tumors. Refinement of differential diagnosis biomarkers, markers for early prognosis of aggressive disease, and therapeutic targets to complement immunotherapy...