Daniel Marbach
Overview
Explore the profile of Daniel Marbach including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
3008
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0
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Recent Articles
1.
Verlingue L, Italiano A, Prenen H, Alia E, Tosi D, Perets R, et al.
EBioMedicine
. 2024 Oct;
109:105374.
PMID: 39395231
Background: Simlukafusp alfa (FAP-IL2v) is an immune cytokine engineered to selectively promote immune responses in the tumour microenvironment. We evaluated the antitumour activity and safety of FAP-IL2v plus atezolizumab in...
2.
Li M, Huang Y, Sumathipala M, Liang M, Valdeolivas A, Ananthakrishnan A, et al.
Nat Methods
. 2024 Jul;
21(8):1546-1557.
PMID: 39039335
Understanding protein function and developing molecular therapies require deciphering the cell types in which proteins act as well as the interactions between proteins. However, modeling protein interactions across biological contexts...
3.
Prenen H, Deva S, Keam B, Lindsay C, Lugowska I, Yang J, et al.
Clin Cancer Res
. 2024 May;
30(14):2945-2953.
PMID: 38709220
Purpose: In this study, we report the results from the esophageal squamous cell carcinoma (SCC) cohort of a phase II, noncomparative, basket study evaluating the antitumor activity and safety of...
4.
Sam J, Hofer T, Kuettel C, Claus C, Thom J, Herter S, et al.
Blood
. 2024 Mar;
143(21):2152-2165.
PMID: 38437725
Effective T-cell responses not only require the engagement of T-cell receptors (TCRs; "signal 1"), but also the availability of costimulatory signals ("signal 2"). T-cell bispecific antibodies (TCBs) deliver a robust...
5.
Li M, Huang Y, Sumathipala M, Liang M, Valdeolivas A, Ananthakrishnan A, et al.
bioRxiv
. 2023 Jul;
PMID: 37503080
Understanding protein function and developing molecular therapies require deciphering the cell types in which proteins act as well as the interactions between proteins. However, modeling protein interactions across biological contexts...
6.
Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, et al.
J Immunother Cancer
. 2022 Nov;
10(11).
PMID: 36319064
Background: Next-generation cancer immunotherapies are designed to broaden the therapeutic repertoire by targeting new immune checkpoints including lymphocyte-activation gene 3 (LAG-3) and T cell immunoglobulin and mucin-domain containing-3 (TIM-3). Yet,...
7.
Gutierrez-Prat N, Zuberer H, Mangano L, Karimaddini Z, Wolf L, Tyanova S, et al.
Life Sci Alliance
. 2022 May;
5(9).
PMID: 35580987
MAPK inhibitors (MAPKi) remain an important component of the standard of care for metastatic melanoma. However, acquired resistance to these drugs limits their therapeutic benefit. Tumor cells can become refractory...
8.
Wellinger L, Hogg S, Newman D, Friess T, Geiss D, Michie J, et al.
Cancer Immunol Res
. 2021 Nov;
10(1):87-107.
PMID: 34782346
Targeting chromatin binding proteins and modifying enzymes can concomitantly affect tumor cell proliferation and survival, as well as enhance antitumor immunity and augment cancer immunotherapies. By screening a small-molecule library...
9.
Reger De Moura C, Prunotto M, Sohail A, Battistella M, Jouenne F, Marbach D, et al.
Front Oncol
. 2020 Oct;
10:1748.
PMID: 33014862
Melanoma is a highly malignant skin cancer with high propensity to metastasize and develop drug resistance, making it a difficult cancer to treat. Current therapies targeting BRAF (V600) mutations are...
10.
Tomasoni M, Gomez S, Crawford J, Zhang W, Choobdar S, Marbach D, et al.
Bioinformatics
. 2020 Apr;
36(12):3920-3921.
PMID: 32271874
Summary: We define a disease module as a partition of a molecular network whose components are jointly associated with one or several diseases or risk factors thereof. Identification of such...