Daniel Hebenstreit
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Explore the profile of Daniel Hebenstreit including associated specialties, affiliations and a list of published articles.
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43
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1145
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Recent Articles
1.
Davies P, Cavallaro M, Hebenstreit D
Cytometry A
. 2025 Mar;
PMID: 40071841
Measuring the size of individual cells in high-throughput experiments is often important in biomedical research and applications. Nevertheless, popular tools for high-throughput single-cell biology, such as flow cytometers, only offer...
2.
Hebenstreit D, Karmakar P
Biochem Soc Trans
. 2024 Aug;
52(4):1695-1702.
PMID: 39119657
Transcription occurs as irregular bursts in a very wide range of systems, including numerous different species and many genes within these. In this review, we examine the underlying theories, discuss...
3.
Callan-Sidat A, Zewdu E, Cavallaro M, Liu J, Hebenstreit D
iScience
. 2024 May;
27(6):109914.
PMID: 38799575
RNA polymerase II (Pol II) has a C-terminal domain (CTD) that is unstructured, consisting of a large number of heptad repeats, and whose precise function remains unclear. Here, we investigate...
4.
Zanin O, Eastham M, Winczura K, Ashe M, Martinez-Nunez R, Hebenstreit D, et al.
Commun Biol
. 2023 Nov;
6(1):1112.
PMID: 37919390
Most functional eukaryotic mRNAs contain a 5' 7-methylguanosine (mG) cap. Although capping is essential for many biological processes including mRNA processing, export and translation, the fate of uncapped transcripts has...
5.
Cavallaro M, Wang Y, Hebenstreit D, Dutta R
R Soc Open Sci
. 2023 Aug;
10(8):221469.
PMID: 37538742
Transcription is a complex phenomenon that permits the conversion of genetic information into phenotype by means of an enzyme called RNA polymerase, which erratically moves along and scans the DNA...
6.
Edwards D, Davies P, Hebenstreit D
Genome Biol
. 2023 Jun;
24(1):138.
PMID: 37328900
Despite the recent rise of RNA-seq datasets combining single-cell (sc) resolution with 4-thiouridine (4sU) labelling, analytical methods exploiting their power to dissect transcriptional bursting are lacking. Here, we present a...
7.
Sledziowska M, Winczura K, Jones M, Almaghrabi R, Mischo H, Hebenstreit D, et al.
Hum Mol Genet
. 2022 Sep;
32(4):608-620.
PMID: 36084040
Mutations and aberrant gene expression during cellular differentiation lead to neurodevelopmental disorders, such as Prader-Willi syndrome (PWS), which results from the deletion of an imprinted locus on paternally inherited chromosome...
8.
Haussmann I, Wu Y, Nallasivan M, Archer N, Bodi Z, Hebenstreit D, et al.
Nat Commun
. 2022 Mar;
13(1):1209.
PMID: 35260552
Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O-methylated at the 2' position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here...
9.
De S, Edwards D, Dwivedi V, Wang J, Varsally W, Dixon H, et al.
Nucleic Acids Res
. 2021 Dec;
50(1):350-367.
PMID: 34928380
Although the RNA helicase Upf1 has hitherto been examined mostly in relation to its cytoplasmic role in nonsense mediated mRNA decay (NMD), here we report high-throughput ChIP data indicating genome-wide...
10.
Zhang J, Cavallaro M, Hebenstreit D
Cell Rep Methods
. 2021 Nov;
1(6):None.
PMID: 34723238
Transcription of many genes in metazoans is subject to polymerase pausing, which is the transient stop of transcriptionally engaged polymerases. This is known to mainly occur in promoter-proximal regions but...