Jutta Horejs-Hoeck
Overview
Explore the profile of Jutta Horejs-Hoeck including associated specialties, affiliations and a list of published articles.
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61
Citations
1458
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Recent Articles
1.
Elmer D, Stockmaier G, Grund-Groschke S, Strobl V, Dang H, Wiederstein M, et al.
Cell Commun Signal
. 2025 Feb;
23(1):91.
PMID: 39962447
Background: Pharmacological targeting of Hedgehog (HH)/GLI has proven effective for certain blood, brain and skin cancers including basal cell carcinoma (BCC). However, limited response rates and the development of drug...
2.
Sieberer H, Luciano M, Amend D, Blochl C, Eglseer A, Steinkellner A, et al.
Cell Commun Signal
. 2025 Jan;
23(1):53.
PMID: 39875995
FLT3 mutations occur in approximately 25% of all acute myeloid leukemia (AML) patients. While several FLT3 inhibitors have received FDA approval, their use is currently limited to combination therapies with...
3.
Ribeiro A, Neuper T, Horejs-Hoeck J
Int J Nanomedicine
. 2024 Oct;
19:10685-10697.
PMID: 39464674
The signaling pathway that comprises cyclic guanosine monophosphate-adenosine monophosphate (cGAMP or GMP-AMP) synthase (cGAS) and Stimulator of Interferon Genes (STING) is emerging as a druggable target for immunotherapy, with tumor-resident...
4.
Neuper T, Frauenlob T, Dang H, Krenn P, Posselt G, Regl C, et al.
Gut Microbes
. 2024 Sep;
16(1):2402543.
PMID: 39288239
Sophisticated immune evasion strategies enable to colonize the gastric mucosa of approximately half of the world's population. Persistent infection and the resulting chronic inflammation are a major cause of gastric...
5.
Luciano M, Sieberer H, Krenn P, Dang H, Vetter J, Neuper T, et al.
Cell Commun Signal
. 2024 Sep;
22(1):424.
PMID: 39223663
Background: Acute myeloid leukemia (AML) is characterized by the abnormal proliferation of myeloid precursor cells and presents significant challenges in treatment due to its heterogeneity. Recently, the NLRP3 inflammasome has...
6.
Bauer R, Dang H, Neureiter D, Unger M, Neuper T, Jensen M, et al.
Front Immunol
. 2024 Jun;
15:1393819.
PMID: 38933263
Introduction & Objective: Allergic sensitization is an essential step in the development of allergic airway inflammation to birch pollen (BP); however, this process remains to be fully elucidated. Recent scientific...
7.
Valsalakumari R, Pandya A, Prasmickaite L, Kvalvaag A, Myrann A, Aslund A, et al.
Int J Nanomedicine
. 2024 Apr;
19:3009-3029.
PMID: 38562610
Background: Biodegradable poly(alkyl cyanoacrylate) (PACA) nanoparticles (NPs) are receiving increasing attention in anti-cancer nanomedicine development not only for targeted cancer chemotherapy, but also for modulation of the tumor microenvironment. We...
8.
Fux A, Melo C, Schlahsa L, Burzan N, Felsberger A, Gessner I, et al.
Int J Mol Sci
. 2024 Feb;
25(4).
PMID: 38396974
Endotoxin, a synonym for lipopolysaccharide (LPS), is anchored in the outer membranes of Gram-negative bacteria. Even minute amounts of LPS entering the circulatory system can have a lethal immunoactivating effect....
9.
Frauenlob T, Neuper T, Regl C, Schaepertoens V, Unger M, Oswald A, et al.
Front Immunol
. 2023 Dec;
14:1290833.
PMID: 38053995
is a widespread Gram-negative pathogen involved in a variety of gastrointestinal diseases, including gastritis, ulceration, mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. Immune responses aimed at eradication of often...
10.
Urwanisch L, Unger M, Sieberer H, Dang H, Neuper T, Regl C, et al.
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831382
Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by altered myeloid progenitor cell proliferation and differentiation. As in many other cancers, epigenetic transcriptional repressors such as histone deacetylases (HDACs)...