Daniel C Farley
Overview
Explore the profile of Daniel C Farley including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
52
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Farley D, McCloskey L, Thorne B, Tareen S, Nicolai C, Campbell D, et al.
Mol Ther Methods Clin Dev
. 2015 Jun;
2:15017.
PMID: 26029728
It is a current regulatory requirement to demonstrate absence of detectable replication-competent lentivirus (RCL) in lentiviral vector products prior to use in clinical trials. Immune Design previously described an HIV-1-based...
2.
Farley D, Bannister R, Leroux-Carlucci M, Evans N, Miskin J, Mitrophanous K
Hum Gene Ther Methods
. 2012 Nov;
23(5):309-23.
PMID: 23121195
The release of lentiviral vectors for clinical use requires the testing of vector material, production cells, and, if applicable, ex vivo-transduced cells for the presence of replication-competent lentivirus (RCL). Vectors...
3.
Morris S, Farley D, Leppard K
BMC Biotechnol
. 2010 Dec;
10:92.
PMID: 21182761
Background: Adenovirus serotype 5 (Ad5) has many favourable characteristics for development as a gene therapy vector. However, the utility of current Ad5 vectors is limited by transient transgene expression, toxicity...
4.
Farley D, Iqball S, Smith J, Miskin J, Kingsman S, Mitrophanous K
J Gene Med
. 2007 Mar;
9(5):345-56.
PMID: 17366519
Pseudotyping viral vectors with vesicular stomatitis virus glycoprotein (VSV-G) enables the transduction of an extensive range of cell types from different species. We have discovered two important parameters of the...
5.
Farley D, Brown J, Leppard K
J Virol
. 2004 Jan;
78(4):1782-91.
PMID: 14747543
The adenovirus major late transcription unit (MLTU) encodes multiple proteins from five regions, L1 to L5, through differential splicing and polyadenylation. MLTU expression is temporally regulated; only a single product...