Dalen Chan
Overview
Explore the profile of Dalen Chan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
153
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0
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Recent Articles
1.
Fitzsimmons C, Mandler M, Lunger J, Chan D, Maligireddy S, Schmiechen A, et al.
NAR Cancer
. 2024 Feb;
6(1):zcae004.
PMID: 38328795
Metabolic reprogramming is a hallmark of cancer that facilitates changes in many adaptive biological processes. Mutations in the tricarboxylic acid cycle enzyme fumarate hydratase (FH) lead to fumarate accumulation and...
2.
Chan D, Feng C, England W, Wyman D, Flynn R, Wang X, et al.
Nucleic Acids Res
. 2021 Oct;
49(20):11868-11882.
PMID: 34634799
RNA molecules can fold into complex structures and interact with trans-acting factors to control their biology. Recent methods have been focused on developing novel tools to measure RNA structure transcriptome-wide,...
3.
Chan D, Fitzsimmons C, Mandler M, Batista P
PLoS Comput Biol
. 2021 Jun;
17(6):e1009057.
PMID: 34166364
No abstract available.
4.
5.
Karner H, Webb C, Carmona S, Liu Y, Lin B, Erhard M, et al.
J Mol Biol
. 2019 Sep;
432(2):283-300.
PMID: 31518612
Long noncoding RNAs (lncRNAs) have been identified in all eukaryotes and are most abundant in the human genome. However, the functional importance and mechanisms of action for human lncRNAs are...
6.
Zinshteyn B, Chan D, England W, Feng C, Green R, Spitale R
Nucleic Acids Res
. 2018 Nov;
47(1):43-55.
PMID: 30476193
Chemical probing methods are crucial to our understanding of the structure and function of RNA molecules. The majority of chemical methods used to probe RNA structure report on Watson-Crick pairing,...
7.
Feng C, Chan D, Joseph J, Muuronen M, Coldren W, Dai N, et al.
Nat Chem Biol
. 2018 Feb;
14(3):325.
PMID: 29443971
This corrects the article DOI: 10.1038/nchembio.2548.
8.
Chan D, Beasley S, Zhen Y, Spitale R
Bioorg Med Chem Lett
. 2018 Feb;
28(4):601-605.
PMID: 29398542
Recent analysis of transcriptomes has revealed that RNA molecules perform a myriad of functions beyond coding for proteins. RNA molecules can fold into complex secondary and tertiary structures, which are...
9.
Feng C, Chan D, Joseph J, Muuronen M, Coldren W, Dai N, et al.
Nat Chem Biol
. 2018 Jan;
14(3):276-283.
PMID: 29334380
The discovery of functional RNAs that are critical for normal and disease physiology continues to expand at a breakneck pace. Many RNA functions are controlled by the formation of specific...
10.