Pedro J Batista
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Explore the profile of Pedro J Batista including associated specialties, affiliations and a list of published articles.
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43
Citations
5787
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Recent Articles
1.
Mandler M, Kulkarni S, Batista P
Mol Cell Biol
. 2025 Jan;
:1-8.
PMID: 39757918
RNA modifications are highly conserved across all domains of life, suggesting an early emergence and a fundamental role in cellular processes. The modification 3-(3-amino-3-carboxypropyl)uridine (acp³U) is found in tRNAs of...
2.
Rabelo-Fernandez R, Yuen M, Batista P
Curr Opin Genet Dev
. 2024 May;
86:102206.
PMID: 38788488
The modification N6-methyladenosine (mA) plays an important role in determining the functional output of gene expression programs. Throughout the transcriptome, the levels of mA are tightly regulated by the opposing...
3.
Mandler M, Maligireddy S, Guiblet W, Fitzsimmons C, McDonald K, Warrell D, et al.
RNA
. 2024 Apr;
30(8):1025-1040.
PMID: 38684317
RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria,...
4.
Gonzalez Dalmasy J, Fitzsimmons C, Frye W, Perciaccante A, Jewell C, Jenkins L, et al.
Chem Biol Interact
. 2024 Apr;
394:110989.
PMID: 38574836
Although few resistance mechanisms for histone deacetylase inhibitors (HDACis) have been described, we recently demonstrated that TMT1A (formerly METTL7A) and TMT1B (formerly METTL7B) can mediate resistance to HDACis with a...
5.
Mandler M, Maligireddy S, Guiblet W, Fitzsimmons C, McDonald K, Warrell D, et al.
bioRxiv
. 2024 Mar;
PMID: 38529508
RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria,...
6.
Fitzsimmons C, Mandler M, Lunger J, Chan D, Maligireddy S, Schmiechen A, et al.
NAR Cancer
. 2024 Feb;
6(1):zcae004.
PMID: 38328795
Metabolic reprogramming is a hallmark of cancer that facilitates changes in many adaptive biological processes. Mutations in the tricarboxylic acid cycle enzyme fumarate hydratase (FH) lead to fumarate accumulation and...
7.
Robey R, Fitzsimmons C, Guiblet W, Frye W, Gonzalez Dalmasy J, Wang L, et al.
Mol Cancer Ther
. 2023 Dec;
23(4):464-477.
PMID: 38151817
Histone deacetylase inhibitors (HDACi) are part of a growing class of epigenetic therapies used for the treatment of cancer. Although HDACis are effective in the treatment of T-cell lymphomas, treatment...
8.
Gonzalez Dalmasy J, Fitzsimmons C, Frye W, Perciaccante A, Jewell C, Jenkins L, et al.
bioRxiv
. 2023 Dec;
PMID: 38076968
Although few resistance mechanisms for histone deacetylase inhibitors (HDACis) have been described, we recently demonstrated that TMT1A (formerly METTL7A) and TMT1B (formerly METTL7B) can mediate resistance to HDACis with a...
9.
Crooks D, Cawthon G, Fitzsimmons C, Perez M, Ricketts C, Vocke C, et al.
Hum Mol Genet
. 2023 Aug;
32(22):3135-3145.
PMID: 37561409
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant condition characterized by the development of cutaneous and uterine leiomyomas and risk for development of an aggressive form of...
10.
Nguyen H, Batista P
Sci China Life Sci
. 2023 Jul;
66(11):2694-2696.
PMID: 37410205
No abstract available.