Ivan R Correa Jr
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Explore the profile of Ivan R Correa Jr including associated specialties, affiliations and a list of published articles.
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77
Citations
2407
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Recent Articles
1.
Fluke K, Dai N, Wolf E, Fuchs R, Ho P, Talbott V, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(45):e2405999121.
PMID: 39471227
Ribosome structure and activity are challenged at high temperatures, often demanding modifications to ribosomal RNAs (rRNAs) to retain translation fidelity. LC-MS/MS, bisulfite-sequencing, and high-resolution cryo-EM structures of the archaeal ribosome...
2.
Fluke K, Fuchs R, Tsai Y, Talbott V, Elkins L, Febvre H, et al.
Nat Commun
. 2024 Aug;
15(1):7272.
PMID: 39179532
RNAs are often modified to invoke new activities. While many modifications are limited in frequency, restricted to non-coding RNAs, or present only in select organisms, 5-methylcytidine (mC) is abundant across...
3.
Vaisvila R, Johnson S, Yan B, Dai N, Bourkia B, Chen M, et al.
Mol Cell
. 2024 Feb;
84(5):854-866.e7.
PMID: 38402612
Deaminases have important uses in modification detection and genome editing. However, the range of applications is limited by the small number of characterized enzymes. To expand the toolkit of deaminases,...
4.
Watson K, Bromley R, Sparklin B, Gasser M, Bhattacharya T, Lebov J, et al.
Life Sci Alliance
. 2023 Nov;
7(2).
PMID: 38030223
RNA modifications, such as methylation, can be detected with Oxford Nanopore Technologies direct RNA sequencing. One commonly used tool for detecting 5-methylcytosine (mC) modifications is Tombo, which uses an "Alternative...
5.
Wolf E, Dai N, Chan S, Correa Jr I
ACS Pharmacol Transl Sci
. 2023 Nov;
6(11):1692-1702.
PMID: 37974627
The 7-methyl guanosine cap structure is an essential 5' end modification of eukaryotic mRNA. It plays a critical role in many aspects of the life cycle of mRNA, including nuclear...
6.
Grunberg S, Doyle L, Wolf E, Dai N, Correa Jr I, Yigit E, et al.
PLoS One
. 2023 Nov;
18(11):e0291267.
PMID: 37939088
The chemical modification of RNA bases represents a ubiquitous activity that spans all domains of life. Pseudouridylation is the most common RNA modification and is observed within tRNA, rRNA, ncRNA...
7.
Lagou V, Jiang L, Ulrich A, Zudina L, Gonzalez K, Balkhiyarova Z, et al.
Nat Genet
. 2023 Sep;
55(9):1448-1461.
PMID: 37679419
Conventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on 'around the clock' glucoregulatory processes. Here we...
8.
Chen Q, Liu B, Zeng Y, Hwang J, Dai N, Correa Jr I, et al.
NAR Cancer
. 2023 May;
5(2):zcad022.
PMID: 37206360
Maintenance of genomic methylation patterns at DNA replication forks by DNMT1 is the key to faithful mitotic inheritance. DNMT1 is often overexpressed in cancer cells and the DNA hypomethylating agents...
9.
Tzertzinis G, Baker B, Benner J, Brown E, Correa Jr I, Ettwiller L, et al.
PLoS One
. 2022 Oct;
17(10):e0276315.
PMID: 36251663
The luciferin sulfokinase (coelenterazine sulfotransferase) of Renilla was previously reported to activate the storage form, luciferyl sulfate (coelenterazine sulfate) to luciferin (coelenterazine), the substrate for the luciferase bioluminescence reaction. The...
10.
Zhang Y, Hunt E, Tamanaha E, Correa Jr I, Tanner N
Commun Biol
. 2022 Sep;
5(1):999.
PMID: 36130997
Detection of nucleic acid amplification has typically required sophisticated laboratory instrumentation, but as the amplification techniques have moved away from the lab, complementary detection techniques have been implemented to facilitate...