D T Denhardt
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Explore the profile of D T Denhardt including associated specialties, affiliations and a list of published articles.
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178
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Recent Articles
1.
Yumoto K, Nifuji A, Rittling S, Tsuchiya Y, Kon S, Uede T, et al.
Cartilage
. 2015 Jun;
3(1):79-85.
PMID: 26069621
Objective: Apoptosis of chondrocytes in articular cartilage has been observed in rheumatoid arthritis patients. However, molecules involved in such chondrocyte apoptosis in arthritic joints have not been fully understood. We...
2.
3.
Porter J, Shen S, Denhardt D
Br J Cancer
. 2004 Jan;
90(2):463-70.
PMID: 14735194
TIMP-1, an approximately 30 kDa glycosylated protein found predominantly in extracellular compartments, is involved in the regulation of a variety of developmental, remodelling, and pathological processes. One function of TIMP-1...
4.
Shapses S, Cifuentes M, Spevak L, Chowdhury H, Brittingham J, Boskey A, et al.
Calcif Tissue Int
. 2003 Sep;
73(1):86-92.
PMID: 14506959
Osteopontin null-mice were previously shown to have bones containing more mineral and larger mineral crystals. These bones were independently seen to be resistant to ovariectomy-induced remodeling. To separate the physicochemical...
5.
Chellaiah M, Kizer N, Biswas R, Alvarez U, Strauss-Schoenberger J, Rifas L, et al.
Mol Biol Cell
. 2003 Jan;
14(1):173-89.
PMID: 12529435
Osteopontin (OPN) was expressed in murine wild-type osteoclasts, localized to the basolateral, clear zone, and ruffled border membranes, and deposited in the resorption pits during bone resorption. The lack of...
6.
Suzuki K, Zhu B, Rittling S, Denhardt D, Goldberg H, McCulloch C, et al.
J Bone Miner Res
. 2002 Aug;
17(8):1486-97.
PMID: 12162503
Although osteopontin (OPN) is recognized generally as a secreted protein, an intracellular form of osteopontin (iOPN), associated with the CD44 complex, has been identified in migrating fibroblastic cells. Because both...
7.
Khan S, Zhang J, Fisher L, Sorensen E, Denhardt D
J Cell Biochem
. 2002 Apr;
85(4):728-36.
PMID: 11968013
Osteopontin (OPN) is primarily an extracellular glycosylated phosphoprotein capable of stimulating cell migration and cell attachment, predominantly to mineralized surfaces. Found in moderate levels in plasma, it acts as a...
8.
Chabas D, Baranzini S, Mitchell D, Bernard C, Rittling S, Denhardt D, et al.
Science
. 2001 Nov;
294(5547):1731-5.
PMID: 11721059
Multiple sclerosis is a demyelinating disease, characterized by inflammation in the brain and spinal cord, possibly due to autoimmunity. Large-scale sequencing of cDNA libraries, derived from plaques dissected from brains...
9.
Denhardt D, Burger E, Kazanecki C, Krishna S, Semeins C, Klein-Nulend J
Biochem Biophys Res Commun
. 2001 Oct;
288(2):448-53.
PMID: 11606063
Osteopontin (OPN) is a noncollagenous component of bone matrix. It mediates cell attachment and activates signal transduction pathways. In this work, bone cells, cultured from fragments of long bones derived...
10.
Denhardt D, Noda M, ORegan A, Pavlin D, Berman J
J Clin Invest
. 2001 May;
107(9):1055-61.
PMID: 11342566
No abstract available.