S R Rittling
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Explore the profile of S R Rittling including associated specialties, affiliations and a list of published articles.
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35
Citations
1988
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Recent Articles
1.
Rittling S, Singh R
J Dent Res
. 2015 Sep;
94(12):1638-45.
PMID: 26341976
Since its initial identification as one of the genes most highly upregulated upon T-cell activation, osteopontin (or Eta-1, as it was designated then) has been demonstrated to have many roles...
2.
Yumoto K, Nifuji A, Rittling S, Tsuchiya Y, Kon S, Uede T, et al.
Cartilage
. 2015 Jun;
3(1):79-85.
PMID: 26069621
Objective: Apoptosis of chondrocytes in articular cartilage has been observed in rheumatoid arthritis patients. However, molecules involved in such chondrocyte apoptosis in arthritic joints have not been fully understood. We...
3.
Rittling S, Wejse P, Yagiz K, Warot G, Hui T
Br J Cancer
. 2014 Jan;
110(5):1269-77.
PMID: 24473400
Background: The integrin-binding protein osteopontin is strongly associated with tumour development, yet is an abundant dietary component as a constituent of human and bovine milk. Therefore, we tested the effect...
4.
Rittling S, Chambers A
Br J Cancer
. 2004 May;
90(10):1877-81.
PMID: 15138464
Since its first identification as a transformation-associated protein, osteopontin (OPN) has been recognised as important in the processes of tumorigenicity and metastasis. Here, we review the evidence that OPN might...
5.
Chellaiah M, Kizer N, Biswas R, Alvarez U, Strauss-Schoenberger J, Rifas L, et al.
Mol Biol Cell
. 2003 Jan;
14(1):173-89.
PMID: 12529435
Osteopontin (OPN) was expressed in murine wild-type osteoclasts, localized to the basolateral, clear zone, and ruffled border membranes, and deposited in the resorption pits during bone resorption. The lack of...
6.
Suzuki K, Zhu B, Rittling S, Denhardt D, Goldberg H, McCulloch C, et al.
J Bone Miner Res
. 2002 Aug;
17(8):1486-97.
PMID: 12162503
Although osteopontin (OPN) is recognized generally as a secreted protein, an intracellular form of osteopontin (iOPN), associated with the CD44 complex, has been identified in migrating fibroblastic cells. Because both...
7.
Chabas D, Baranzini S, Mitchell D, Bernard C, Rittling S, Denhardt D, et al.
Science
. 2001 Nov;
294(5547):1731-5.
PMID: 11721059
Multiple sclerosis is a demyelinating disease, characterized by inflammation in the brain and spinal cord, possibly due to autoimmunity. Large-scale sequencing of cDNA libraries, derived from plaques dissected from brains...
8.
Nemoto H, Rittling S, Yoshitake H, Furuya K, Amagasa T, Tsuji K, et al.
J Bone Miner Res
. 2001 Apr;
16(4):652-9.
PMID: 11315992
Osteopontin has been implicated in the metastasis of tumors, and human tumors with high metastatic activity often express osteopontin at high levels. Osteopontin contains an arginine-glycine-aspartate (RGD) motif that is...
9.
Ihara H, Denhardt D, Furuya K, Yamashita T, Muguruma Y, Tsuji K, et al.
J Biol Chem
. 2001 Mar;
276(16):13065-71.
PMID: 11278791
Osteopontin is an RGDS-containing protein that acts as a ligand for the alpha(v)beta(3) integrin, which is abundantly expressed in osteoclasts, cells responsible for bone resorption in osteopenic diseases such as...
10.
Denhardt D, Giachelli C, Rittling S
Annu Rev Pharmacol Toxicol
. 2001 Mar;
41:723-49.
PMID: 11264474
Osteopontin (OPN) is a glycosylated phosphoprotein found in all body fluids and in the proteinaceous matrix of mineralized tissues. It can function both as a cell attachment protein and as...