D R Edwards
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Explore the profile of D R Edwards including associated specialties, affiliations and a list of published articles.
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Articles
121
Citations
3180
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Recent Articles
1.
Berger Gillam T, Chin J, Cossey S, Culley K, Davidson R, Edwards D, et al.
J Public Health (Oxf)
. 2021 Apr;
43(4):e749-e750.
PMID: 33839796
No abstract available.
2.
Edwards D, Pope L, Berry S
J Laryngol Otol
. 2021 Jan;
135(3):259-263.
PMID: 33509309
Objective: Treatment of locally advanced hypopharyngeal cancer can cause significant morbidity and late toxicity. Pharyngo-laryngo-oesophagectomy can achieve adequate surgical margins, but data on survival and functional outcome are limited, especially...
3.
Piddock R, Loughran N, Marlein C, Robinson S, Edwards D, Yu S, et al.
Blood Cancer J
. 2017 Mar;
7(3):e539.
PMID: 28282033
Phosphoinositide-3-kinase and protein kinase B (PI3K-AKT) is upregulated in multiple myeloma (MM). Using a combination of short hairpin RNA (shRNA) lentivirus-mediated knockdown and pharmacologic isoform-specific inhibition we investigated the role...
4.
Jenkinson S, Brown L, Ombor J, Milburn J, Smulders-Srinivasan T, Veuger S, et al.
Biochim Biophys Acta Mol Cell Res
. 2016 Nov;
1864(2):336-344.
PMID: 27888098
Maspin is a non-inhibitory member of the serpin family that affects cell behaviours related to migration and survival. We have previously shown that peptides of the isolated G α-helix (G-helix)...
5.
Thorne C, Roberts L, Edwards D, Haque M, Cumbassa A, Last A
Paediatr Int Child Health
. 2013 Aug;
33(3):151-60.
PMID: 23930727
Background: Childhood malnutrition is the leading risk factor for the global burden of disease. Guinea-Bissau is a politically unstable country with high levels of childhood malnutrition and mortality. Aim: To...
6.
Baren J, Stewart G, Stokes A, Gray K, Pennington C, ONeill R, et al.
Br J Cancer
. 2012 Jun;
107(1):143-9.
PMID: 22677901
Background: Degradation of the extracellular matrix is fundamental to tumour development, invasion and metastasis. Several protease families have been implicated in the development of a broad range of tumour types,...
7.
Robertson M, Abou-Saleh M, Harrison D, Nairac B, Edwards D, Lock T, et al.
J Psychopharmacol
. 2012 Feb;
8(2):98-103.
PMID: 22298536
One hundred and eighty three patients with DSM-III-R major depressive illness were allocated randomly to treatment with one of two new generation antidepressants, fluoxetine and lofepramine. Both patient groups had...
8.
Ramsay A, McCracken S, Soofi M, FLEMING J, Yu A, Ahmad I, et al.
Br J Cancer
. 2011 Jan;
104(4):664-72.
PMID: 21266977
Background: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)-extracellular signal-regulated protein kinase 5 (ERK5)-mediated signalling has been implicated in a number of tumour types including prostate cancer (PCa). The molecular basis of...
9.
Stewart G, Skipworth R, Pennington C, Lowrie A, Deans D, Edwards D, et al.
Br J Cancer
. 2008 Jul;
99(1):126-32.
PMID: 18594538
Dermcidin acts as a survival factor in a variety of cancer cell lines under hypoxia or oxidative stress. The aim of this study was to evaluate dermcidin expression in cell...
10.
Atkinson J, Pennington C, Martin S, Anikin V, Mearns A, Loadman P, et al.
Eur J Cancer
. 2007 Jun;
43(11):1764-71.
PMID: 17600697
Improved understanding of the involvement of matrix metalloproteinases (MMPs), including membrane-type MMPs (MT-MMPs), in human tumours has potential diagnostic, prognostic and therapeutic implications. We assessed the relationship between MT-MMP expression...