D D Chaplin
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Explore the profile of D D Chaplin including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Jung Y, Wen T, Mingler M, Caldwell J, Wang Y, Chaplin D, et al.
Mucosal Immunol
. 2015 Jan;
8(4):930-42.
PMID: 25563499
Eosinophils are multifunctional leukocytes that reside in the gastrointestinal (GI) lamina propria, where their basal function remains largely unexplored. In this study, by examining mice with a selective deficiency of...
2.
Nabe T, Matsuya K, Akamizu K, Fujita M, Nakagawa T, Shioe M, et al.
Br J Pharmacol
. 2013 Mar;
169(2):462-76.
PMID: 23472967
Background And Purpose: Mast cell hyperplasia has been observed in the lungs of mice with experimental asthma, but few reports have studied basophils. Here, we attempted to discriminate and quantify...
3.
Alberti M, Deshane J, Chaplin D, Pereboeva L, Curiel D, Roth J
Gene Ther
. 2012 Nov;
20(7):733-41.
PMID: 23171918
Specific and efficient gene delivery to the lung has been hampered by liver sequestration of adenovirus serotype 5 (Ad5) vectors. The complexity of Ad5 liver tropism has largely been unraveled,...
4.
Deshane J, Zmijewski J, Luther R, Gaggar A, Deshane R, Lai J, et al.
Mucosal Immunol
. 2011 Apr;
4(5):503-18.
PMID: 21471960
Levels of reactive free radicals are elevated in the airway during asthmatic exacerbations, but their roles in the pathophysiology of asthma remain unclear. We have identified subsets of myeloid-derived suppressor-like...
5.
Chaplin D, Brownstein B
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 6:Unit6.9.
PMID: 18265264
This unit provides an introduction to the use of yeast artificial chromosome-bearing yeast clones (hereafter referred to as YAC clones) in genome analysis. It describes criteria for designing a polymerase...
6.
Chaplin D, Brownstein B
Curr Protoc Mol Biol
. 2008 Feb;
Chapter 6:Unit6.10.
PMID: 18265255
This unit provides a series of protocols describing the analysis and manipulation of an isolated YAC clone. The procedures are based upon the use of the YAC vector pYAC4. Once...
7.
Byersdorfer C, Chaplin D
J Immunol
. 2001 Dec;
167(12):6756-64.
PMID: 11739490
We have used fluorescent latex beads, with or without covalently conjugated OVA, to facilitate study of Ag trafficking in the mouse lung and draining peribronchial lymph node (LN). At 6...
8.
Shornick L, Bisarya A, Chaplin D
Cell Immunol
. 2001 Oct;
211(2):105-12.
PMID: 11591114
IL-1beta(-/-) mice manifest an impaired contact hypersensitivity response to the hapten trinitrochlorobenzene, with the principle defect expressed during the sensitization phase of this response. Following application of hapten to the...
9.
MASON J, Suzuki K, Chaplin D, Matsushima G
J Neurosci
. 2001 Sep;
21(18):7046-52.
PMID: 11549714
Interleukin-1beta (IL-1beta) is a proinflammatory cytokine associated with the pathophysiology of demyelinating disorders such as multiple sclerosis and viral infections of the CNS. However, we demonstrate here that IL-1beta appears...
10.
Dube P, Revell P, Chaplin D, Lorenz R, Miller V
Proc Natl Acad Sci U S A
. 2001 Aug;
98(19):10880-5.
PMID: 11526216
Infection with pathogenic microbes often results in a significant inflammatory response. A cascade of proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha) and IL-1 initiates this response. Although there is...