Curtis J Bare
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Explore the profile of Curtis J Bare including associated specialties, affiliations and a list of published articles.
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10
Citations
311
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Recent Articles
1.
Xu X, Mendoza A, Krumm C, Su S, Acuna M, Bare C, et al.
Sci Signal
. 2024 Dec;
17(865):eadk7971.
PMID: 39626011
Activation of thermogenic brown adipose tissue (BAT) and inducible beige adipose tissue (BeAT) is triggered by environmental or metabolic stimuli, including cold ambient temperatures and nutrient stress. Thioesterase superfamily member...
2.
Queiroz A, Dantas E, Ramsamooj S, Murthy A, Ahmed M, Zunica E, et al.
Nat Commun
. 2022 Aug;
13(1):4633.
PMID: 35941104
Cancer cachexia is a common, debilitating condition with limited therapeutic options. Using an established mouse model of lung cancer, we find that cachexia is characterized by reduced food intake, spontaneous...
3.
Krumm C, Xu X, Bare C, Holman C, Kersten S, Dow L, et al.
J Biol Chem
. 2021 May;
297(1):100815.
PMID: 34023388
Cyclic AMP-responsive element-binding protein H (CREBH encoded by Creb3l3) is a transcription factor that regulates the expression of genes that control lipid and glucose metabolism as well as inflammation. CREBH...
4.
Krisko T, Nicholls H, Bare C, Holman C, Putzel G, Jansen R, et al.
Cell Metab
. 2020 Feb;
31(3):592-604.e9.
PMID: 32084379
Recent studies suggest that a key mechanism whereby the gut microbiome influences energy balance and glucose homeostasis is through the recruitment of brown and beige adipocytes, primary mediators of the...
5.
Sinden D, Holman C, Bare C, Sun X, Gade A, Cohen D, et al.
FASEB J
. 2019 Jul;
33(10):11579-11594.
PMID: 31339804
Fibroblast growth factor (FGF)13, a nonsecreted, X-linked, FGF homologous factor, is differentially expressed in adipocytes in response to diet, yet 's role in metabolism has not been explored. Heterozygous knockouts...
6.
Xu X, Krumm C, So J, Bare C, Holman C, Gromada J, et al.
Hepatology
. 2018 Apr;
68(6):2167-2181.
PMID: 29698569
Integrated stress response (ISR) is a signaling system in which phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by stress-specific kinases and subsequent activation of activation transcription factor (ATF) 4...
7.
Staffas A, Burgos da Silva M, Slingerland A, Lazrak A, Bare C, Holman C, et al.
Cell Host Microbe
. 2018 Mar;
23(4):447-457.e4.
PMID: 29576480
Bone marrow transplantation (BMT) offers curative potential for patients with high-risk hematologic malignancies, but the post-transplantation period is characterized by profound immunodeficiency. Recent studies indicate that the intestinal microbiota not...
8.
Desai A, Alves-Bezerra M, Li Y, Ozdemir C, Bare C, Li Y, et al.
J Lipid Res
. 2017 Dec;
59(2):368-379.
PMID: 29208699
Thioesterase superfamily member 1 (Them1) is an acyl-CoA thioesterase that is highly expressed in brown adipose tissue, where it functions to suppress energy expenditure. Lower Them1 expression levels in the...
9.
Kazak L, Chouchani E, Lu G, Jedrychowski M, Bare C, Mina A, et al.
Cell Metab
. 2017 Oct;
26(4):693.
PMID: 28978428
No abstract available.
10.
Kazak L, Chouchani E, Lu G, Jedrychowski M, Bare C, Mina A, et al.
Cell Metab
. 2017 Aug;
26(4):660-671.e3.
PMID: 28844881
Diet-induced thermogenesis is an important homeostatic mechanism that limits weight gain in response to caloric excess and contributes to the relative stability of body weight in most individuals. We previously...