Colin J Jackson
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Explore the profile of Colin J Jackson including associated specialties, affiliations and a list of published articles.
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168
Citations
2961
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Recent Articles
1.
He J, Illingworth H, Ullrich S, Ghosh P, Ton J, Jackson C, et al.
Bioorg Med Chem Lett
. 2025 Mar;
:130176.
PMID: 40081602
Alphaviruses like the Chikungunya virus cause severe outbreaks; however, no specific treatments are available. Their viral replication depends on the nsP2 cysteine protease, a promising but underexplored target for drug...
2.
Kaczmarski J, Jackson C, Cockburn I
Trends Parasitol
. 2025 Feb;
PMID: 39984355
Current malaria vaccines provide suboptimal, waning protection. Dacon et al. identify a protective post-translationally modified epitope on Plasmodium sporozoites that is absent from current vaccines. This discovery deepens our understanding...
3.
Bibi S, Breeze C, Jadoon V, Fareed A, Syed A, Frkic R, et al.
Sci Rep
. 2025 Jan;
15(1):3499.
PMID: 39875461
Malachite green (MG) is used as a dye for materials such as wood, cotton, and nylon, and is used in aquaculture to prevent fungal and protozoan diseases. However, it is...
4.
Qianzhu H, Abdelkader E, Welegedara A, Habel E, Paul N, Frkic R, et al.
Angew Chem Int Ed Engl
. 2024 Dec;
64(10):e202421000.
PMID: 39632265
Cyanotryptophans (CN-Trp) are privileged multimodal reporters on protein structure. They are similar in size to the canonical amino acid tryptophan and some of them exhibit bright fluorescence which responds sensitively...
5.
Frkic R, Tan Y, Maleckis A, Chilton N, Otting G, Jackson C
Biochemistry
. 2024 Sep;
63(20):2602-2608.
PMID: 39316701
(2,3)-4-Fluorovaline (FVal) is an analogue of valine, where a single CH group is substituted by a CHF group. In the absence of valine, valyl-tRNA synthetase uses FVal as a substitute,...
6.
Clifton B, Alcolombri U, Uechi G, Jackson C, Laurino P
Nature
. 2024 Sep;
634(8034):721-728.
PMID: 39261732
SAR11 bacteria are the most abundant microorganisms in the surface ocean and have global biogeochemical importance. To thrive in their competitive oligotrophic environment, these bacteria rely heavily on solute-binding proteins...
7.
Kambali M, Li Y, Unichenko P, Feria Pliego J, Yadav R, Liu J, et al.
Mol Psychiatry
. 2024 Aug;
30(3):927-942.
PMID: 39210012
Glycine is an obligatory co-agonist at excitatory NMDA receptors in the brain, especially in the dentate gyrus, which has been postulated to be crucial for the development of psychotic associations...
8.
Carter B, Day G, Zhang W, Sessions R, Jackson C, Perriman A
Small
. 2024 Jul;
20(44):e2401982.
PMID: 38992997
Most organophosphates (OPs) are hydrophobic, and after exposure, can sequester into lipophilic regions within the body, such as adipose tissue, resulting in long term chronic effects. Consequently, there is an...
9.
Saunders J, Damry A, Vongsouthi V, Spence M, Frkic R, Gomez C, et al.
Biochemistry
. 2024 Jun;
63(13):1663-1673.
PMID: 38885634
The mono(2-hydroxyethyl) terephthalate hydrolase (MHETase) from carries out the second step in the enzymatic depolymerization of poly(ethylene terephthalate) (PET) plastic into the monomers terephthalic acid (TPA) and ethylene glycol (EG)....
10.
Harrison K, Carlos P, Ullrich S, Aggarwal A, Johansen-Leete J, Sasi V, et al.
Chemistry
. 2024 May;
30(44):e202401606.
PMID: 38801240
The development of novel antivirals is crucial not only for managing current COVID-19 infections but for addressing potential future zoonotic outbreaks. SARS-CoV-2 main protease (M) is vital for viral replication...