Cody Kelley
Overview
Explore the profile of Cody Kelley including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
578
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Recent Articles
1.
Beckish L, Ging M, Mosman M, Kelley C, Wilkin L, Wills O, et al.
J Orthop Physician Assist
. 2025 Jan;
12(3).
PMID: 39759267
Legg-Calvé-Perthes Disease (LCPD) is a condition marked by temporary blood flow disruption to the proximal femur, commonly afflicting children aged 15 and younger. The etiology of the disease is often...
2.
Kelley C, Lu S, Parhi A, Kaul M, Pilch D, LaVoie E
Eur J Med Chem
. 2013 Jan;
60:395-409.
PMID: 23314053
Bacterial cell division occurs in conjunction with the formation of a cytokinetic Z-ring structure comprised of FtsZ subunits. Agents that can disrupt Z-ring formation have the potential, through this unique...
3.
Kelley C, Zhang Y, Parhi A, Kaul M, Pilch D, LaVoie E
Bioorg Med Chem
. 2012 Nov;
20(24):7012-29.
PMID: 23127490
The emergence of multidrug-resistant bacteria has created an urgent need for antibiotics with a novel mechanism of action. The bacterial cell division protein FtsZ is an attractive target for the...
4.
Parhi A, Kelley C, Kaul M, Pilch D, LaVoie E
Bioorg Med Chem Lett
. 2012 Oct;
22(23):7080-3.
PMID: 23084900
Antibiotic resistance has prompted efforts to discover antibiotics with novel mechanisms of action. FtsZ is an essential protein for bacterial cell division, and has been viewed as an attractive target...
5.
Parhi A, Lu S, Kelley C, Kaul M, Pilch D, LaVoie E
Bioorg Med Chem Lett
. 2012 Oct;
22(22):6962-6.
PMID: 23058886
Berberine is a substituted dibenzo[a,g]quinolizin-7-ium derivative whose modest antibiotic activity is derived from its disruptive impact on the function of the essential bacterial cell division protein FtsZ. The present study...
6.
Marquis K, Comery T, Jow F, Navarra R, Grauer S, Pulicicchio C, et al.
Psychopharmacology (Berl)
. 2011 Jun;
218(4):635-47.
PMID: 21643676
Rationale: α7 nicotinic acetylcholine receptor (nAChR) agonists are proposed as candidate agents for the adjunctive treatment of cognitive deficits associated with schizophrenia. Despite the pursuit of such an approach clinically,...
7.
Kelly M, Logue S, Brennan J, Day J, Lakkaraju S, Jiang L, et al.
Proc Natl Acad Sci U S A
. 2010 Apr;
107(18):8457-62.
PMID: 20404172
Phosphodiesterase 11A (PDE11A) is the most recently identified family of phosphodiesterases (PDEs), the only known enzymes to break down cyclic nucleotides. The tissue expression profile of this dual specificity PDE...
8.
Cole D, Gross J, Comery T, Aschmies S, Hirst W, Kelley C, et al.
Bioorg Med Chem Lett
. 2010 Jan;
20(3):1237-40.
PMID: 20042333
Using a focused screen of biogenic amine compounds we identified a novel series of H(3)R antagonists. A preliminary SAR study led to reduction of MW while increasing binding affinity and...
9.
Grauer S, Pulito V, Navarra R, Kelly M, Kelley C, Graf R, et al.
J Pharmacol Exp Ther
. 2009 Aug;
331(2):574-90.
PMID: 19661377
Following several recent reports that suggest that dual cAMP and cGMP phosphodiesterase 10A (PDE10A) inhibitors may present a novel mechanism to treat positive symptoms of schizophrenia, we sought to extend...
10.
Roncarati R, Scali C, Comery T, Grauer S, Aschmi S, Bothmann H, et al.
J Pharmacol Exp Ther
. 2009 Feb;
329(2):459-68.
PMID: 19223665
The alpha7 nicotinic acetylcholine receptor (nAChR) is a promising target for treatment of cognitive dysfunction associated with Alzheimer's disease and schizophrenia. Here, we report the pharmacological properties of 5-morpholin-4-yl-pentanoic acid...