Claus Scheidereit
Overview
Explore the profile of Claus Scheidereit including associated specialties, affiliations and a list of published articles.
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55
Citations
3145
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Recent Articles
11.
Mikuda N, Schmidt-Ullrich R, Kargel E, Golusda L, Wolf J, Hopken U, et al.
J Pathol
. 2020 Mar;
251(2):160-174.
PMID: 32222043
The IκB kinase (IKK)-NF-κB signaling pathway plays a multifaceted role in inflammatory bowel disease (IBD): on the one hand, it protects from apoptosis; on the other, it activates transcription of...
12.
Hahn A, Kny M, Pablo-Tortola C, Todiras M, Willenbrock M, Schmidt S, et al.
J Cachexia Sarcopenia Muscle
. 2019 Aug;
11(1):103-119.
PMID: 31441598
Background: Critically ill patients frequently develop muscle atrophy and weakness in the intensive-care-unit setting [intensive care unit-acquired weakness (ICUAW)]. Sepsis, systemic inflammation, and acute-phase response are major risk factors. We...
13.
von Hoff L, Kargel E, Franke V, McShane E, Schulz-Beiss K, Patone G, et al.
Blood
. 2019 Jan;
133(13):1489-1494.
PMID: 30696620
Persistent NF-κB activation is a hallmark of the malignant Hodgkin/Reed-Sternberg (HRS) cells in classical Hodgkin lymphoma (cHL). Genomic lesions, Epstein-Barr virus infection, soluble factors, and tumor-microenvironment interactions contribute to this...
14.
Mikuda N, Kolesnichenko M, Beaudette P, Popp O, Uyar B, Sun W, et al.
EMBO J
. 2018 Nov;
37(24).
PMID: 30467221
The IκB kinase (IKK) is considered to control gene expression primarily through activation of the transcription factor NF-κB. However, we show here that IKK additionally regulates gene expression on post-transcriptional...
15.
Schleussner N, Merkel O, Costanza M, Liang H, Hummel F, Romagnani C, et al.
Leukemia
. 2018 Mar;
32(9):1994-2007.
PMID: 29588546
Transcription factor AP-1 is constitutively activated and IRF4 drives growth and survival in ALK and ALK anaplastic large cell lymphoma (ALCL). Here we demonstrate high-level BATF and BATF3 expression in...
16.
Krieger K, Millar S, Mikuda N, Krahn I, Kloepper J, Bertolini M, et al.
J Invest Dermatol
. 2017 Sep;
138(2):256-264.
PMID: 28942365
The transcription factor NF-κB controls key features of hair follicle (HF) development, but the role of NF-κB in adult HF cycle regulation remains obscure. Using NF-κB reporter mouse models, strong...
17.
Choi M, Schreiber A, Eulenberg-Gustavus C, Scheidereit C, Kamps J, Kettritz R
J Am Soc Nephrol
. 2017 Jul;
28(11):3191-3204.
PMID: 28687535
ANCA-associated vasculitis (AAV) is a highly inflammatory condition in which ANCA-activated neutrophils interact with the endothelium, resulting in necrotizing vasculitis. We tested the hypothesis that endothelial NF-B mediates necrotizing crescentic...
18.
de Oliveira K, Kaergel E, Heinig M, Fontaine J, Patone G, Muro E, et al.
Genome Med
. 2016 Mar;
8(1):28.
PMID: 26988706
Background: NF-κB is widely involved in lymphoid malignancies; however, the functional roles and specific transcriptomes of NF-κB dimers with distinct subunit compositions have been unclear. Methods: Using combined ChIP-sequencing and...
19.
Tomann P, Paus R, Millar S, Scheidereit C, Schmidt-Ullrich R
Development
. 2016 Mar;
143(9):1512-22.
PMID: 26952977
In the epidermis of mice lacking transcription factor nuclear factor-kappa B (NF-κB) activity, primary hair follicle (HF) pre-placode formation is initiated without progression to proper placodes. NF-κB modulates WNT and...
20.
Marko L, Vigolo E, Hinze C, Park J, Roel G, Balogh A, et al.
J Am Soc Nephrol
. 2016 Jan;
27(9):2658-69.
PMID: 26823548
NF-κB is a key regulator of innate and adaptive immunity and is implicated in the pathogenesis of AKI. The cell type-specific functions of NF-κB in the kidney are unknown; however,...