Claudia J Laskowski
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Explore the profile of Claudia J Laskowski including associated specialties, affiliations and a list of published articles.
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5
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601
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Recent Articles
1.
Tedeschi A, Dupraz S, Curcio M, Laskowski C, Schaffran B, Flynn K, et al.
Neuron
. 2019 Aug;
103(6):1073-1085.e6.
PMID: 31400829
Injured axons fail to regenerate in the adult CNS, which contrasts with their vigorous growth during embryonic development. We explored the potential of re-initiating axon extension after injury by reactivating...
2.
Tedeschi A, Dupraz S, Laskowski C, Xue J, Ulas T, Beyer M, et al.
Neuron
. 2016 Oct;
92(2):419-434.
PMID: 27720483
Injuries to the adult CNS often result in permanent disabilities because neurons lose the ability to regenerate their axon during development. Here, whole transcriptome sequencing and bioinformatics analysis followed by...
3.
Puttagunta R, Tedeschi A, Soria M, Hervera A, Lindner R, Rathore K, et al.
Nat Commun
. 2014 Apr;
5:3527.
PMID: 24686445
Axonal regenerative failure is a major cause of neurological impairment following central nervous system (CNS) but not peripheral nervous system (PNS) injury. Notably, PNS injury triggers a coordinated regenerative gene...
4.
Laskowski C, Bradke F
Exp Neurol
. 2012 Jul;
242:11-7.
PMID: 22836145
Upon spinal cord injury, severed axons and the surrounding tissue undergo a series of pathological changes, including retraction of proximal axon ends, degeneration of distal axon ends and formation of...
5.
Hellal F, Hurtado A, Ruschel J, Flynn K, Laskowski C, Umlauf M, et al.
Science
. 2011 Jan;
331(6019):928-31.
PMID: 21273450
Hypertrophic scarring and poor intrinsic axon growth capacity constitute major obstacles for spinal cord repair. These processes are tightly regulated by microtubule dynamics. Here, moderate microtubule stabilization decreased scar formation...