Claudia Egerer-Sieber
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Explore the profile of Claudia Egerer-Sieber including associated specialties, affiliations and a list of published articles.
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13
Citations
497
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Recent Articles
1.
Schweininger J, Kriegel M, Hage S, Conrad M, Alkhashrom S, Losing J, et al.
J Biol Chem
. 2022 Jan;
298(3):101625.
PMID: 35074430
Varicella-zoster virus (VZV) is a human pathogen from the α-subfamily of herpesviruses. The VZV Orf24-Orf27 complex represents the essential viral core nuclear egress complex (NEC) that orchestrates the egress of...
2.
Muller Y, Hage S, Alkhashrom S, Hollriegl T, Weigert S, Dolles S, et al.
J Biol Chem
. 2020 Jan;
295(10):3189-3201.
PMID: 31980459
Herpesviruses uniquely express two essential nuclear egress-regulating proteins forming a heterodimeric basic structure of the nuclear egress complex (core NEC). These core NECs serve as a hexameric lattice-structured platform for...
3.
Kirchweger P, Weiler S, Egerer-Sieber C, Blasl A, Hoffmann S, Schmidt C, et al.
Mol Microbiol
. 2019 Aug;
112(5):1403-1422.
PMID: 31419359
Salmonella invasion is mediated by a concerted action of the Salmonella pathogenicity island 4 (SPI4)-encoded type one secretion system (T1SS) and the SPI1-encoded type three secretion system (T3SS-1). The SPI4-encoded...
4.
Schmidt K, Petersen J, Munkert J, Egerer-Sieber C, Hornig M, Muller Y, et al.
Phytochemistry
. 2018 Sep;
156:9-19.
PMID: 30172078
PRISEs (progesterone 5β-reductase and/or iridoid synthase-like 1,4-enone reductases) are involved in cardenolide and iridoid biosynthesis. We here investigated a PRISE (rAtSt5βR) from Arabidopsis thaliana, a plant producing neither cardenolides nor...
5.
Heilingloh C, Klingl S, Egerer-Sieber C, Schmid B, Weiler S, Muhl-Zurbes P, et al.
J Mol Biol
. 2017 Mar;
429(8):1227-1243.
PMID: 28315353
CD83 is a type-I membrane protein and an efficient marker for identifying mature dendritic cells. Whereas membrane-bound, full-length CD83 co-stimulates the immune system, a soluble variant (sCD83), consisting of the...
6.
Rudolph K, Parthier C, Egerer-Sieber C, Geiger D, Muller Y, Kreis W, et al.
Acta Crystallogr F Struct Biol Commun
. 2016 Jan;
72(Pt 1):16-23.
PMID: 26750479
The biosynthesis of γ-terpinene, a precursor of the phenolic isomers thymol and carvacrol found in the essential oil from Thymus sp., is attributed to the activitiy of γ-terpinene synthase (TPS)....
7.
Walzer S, Egerer-Sieber C, Sticht H, Sevvana M, Hohl K, Milbradt J, et al.
J Biol Chem
. 2015 Oct;
290(46):27452-8.
PMID: 26432641
Nuclear replication of cytomegalovirus relies on elaborate mechanisms of nucleocytoplasmic egress of viral particles. Thus, the role of two essential and conserved viral nuclear egress proteins, pUL50 and pUL53, is...
8.
Christoffersen C, Obinata H, Kumaraswamy S, Galvani S, Ahnstrom J, Sevvana M, et al.
Proc Natl Acad Sci U S A
. 2011 May;
108(23):9613-8.
PMID: 21606363
Protection of the endothelium is provided by circulating sphingosine-1-phosphate (S1P), which maintains vascular integrity. We show that HDL-associated S1P is bound specifically to both human and murine apolipoprotein M (apoM)....
9.
Sevvana M, Ahnstrom J, Egerer-Sieber C, Lange H, Dahlback B, Muller Y
J Mol Biol
. 2009 Sep;
393(4):920-36.
PMID: 19733574
Apolipoprotein M (ApoM) is a 25-kDa HDL-associated apolipoprotein and a member of the lipocalin family of proteins. Mature apoM retains its signal peptide, which serves as a lipid anchor attaching...
10.
Resch M, Striegl H, Henssler E, Sevvana M, Egerer-Sieber C, Schiltz E, et al.
Nucleic Acids Res
. 2008 Jul;
36(13):4390-401.
PMID: 18587152
Today's proteome is the result of innumerous gene duplication, mutagenesis, drift and selection processes. Whereas random mutagenesis introduces predominantly only gradual changes in protein function, a case can be made...