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Sigrid Weiler

Explore the profile of Sigrid Weiler including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 630
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Recent Articles
1.
Vockenhuber M, Hoetzel J, Maurer L, Frohlich P, Weiler S, Muller Y, et al.
ACS Synth Biol . 2023 Dec; 13(1):319-327. PMID: 38127784
Progress in the synthetic biology field is driven by the development of new tools for synthetic circuit engineering. Traditionally, the focus has relied on protein-based designs. In recent years, the...
2.
Schweininger J, Kriegel M, Hage S, Conrad M, Alkhashrom S, Losing J, et al.
J Biol Chem . 2022 Jan; 298(3):101625. PMID: 35074430
Varicella-zoster virus (VZV) is a human pathogen from the α-subfamily of herpesviruses. The VZV Orf24-Orf27 complex represents the essential viral core nuclear egress complex (NEC) that orchestrates the egress of...
3.
Kirchweger P, Weiler S, Egerer-Sieber C, Blasl A, Hoffmann S, Schmidt C, et al.
Mol Microbiol . 2019 Aug; 112(5):1403-1422. PMID: 31419359
Salmonella invasion is mediated by a concerted action of the Salmonella pathogenicity island 4 (SPI4)-encoded type one secretion system (T1SS) and the SPI1-encoded type three secretion system (T3SS-1). The SPI4-encoded...
4.
Heilingloh C, Klingl S, Egerer-Sieber C, Schmid B, Weiler S, Muhl-Zurbes P, et al.
J Mol Biol . 2017 Mar; 429(8):1227-1243. PMID: 28315353
CD83 is a type-I membrane protein and an efficient marker for identifying mature dendritic cells. Whereas membrane-bound, full-length CD83 co-stimulates the immune system, a soluble variant (sCD83), consisting of the...
5.
Diestel U, Resch M, Meinhardt K, Weiler S, Hellmann T, Mueller T, et al.
PLoS One . 2013 Jul; 8(6):e67214. PMID: 23826237
The zona pellucida (ZP) domain is present in extracellular proteins such as the zona pellucida proteins and tectorins and participates in the formation of polymeric protein networks. However, the ZP...
6.
Sevvana M, Kassler K, Ahnstrom J, Weiler S, Dahlback B, Sticht H, et al.
J Mol Biol . 2010 Oct; 404(3):363-71. PMID: 20932978
Mouse apolipoprotein M (m-apoM) displays a 79% sequence identity to human apolipoprotein M (h-apoM). Both proteins are apolipoproteins associated with high-density lipoproteins, with similar anticipated biological functions. The structure of...
7.
Stiebritz M, Wengrzik S, Klein D, Richter J, Srebrzynski A, Weiler S, et al.
J Mol Biol . 2010 Sep; 403(3):371-85. PMID: 20816982
The specificity and selectivity of protein-protein interactions are of central importance for many biological processes, including signal transduction and transcription control. We used the in-house side-chain packing program MUMBO to...
8.
Mueller S, Jung R, Weiler S, Lang S
J Gen Virol . 2004 Oct; 85(Pt 11):3291-3303. PMID: 15483243
vpx genes of human immunodeficiency virus type 2 (HIV-2) and immunodeficiency viruses from macaques (SIVmac), sooty mangabeys (SIVsm) and red-capped mangabeys (SIVrcm) encode a 112 aa protein that is packed...
9.
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, Karsten U, et al.
Mol Cell Biol . 2002 Jan; 22(4):1184-93. PMID: 11809809
Activation of Wnt signaling through beta-catenin/TCF complexes is a key event in the development of various tumors, in particular colorectal and liver tumors. Wnt signaling is controlled by the negative...