Chuanlong Guo
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Explore the profile of Chuanlong Guo including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
387
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Recent Articles
1.
Gao X, Jiang T, Wu X, Li Y, Xiao J, Long L, et al.
Int J Biol Macromol
. 2025 Mar;
:141976.
PMID: 40086544
Cervical cancer remains one of the leading causes of mortality among women, and immunotherapy targeting the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway holds promise for its treatment....
2.
Du T, Wu J, Wang W, Liang W, Li Y, Guo C, et al.
Eur J Med Chem
. 2025 Jan;
286:117316.
PMID: 39874632
A novel class of 7-phenyl-[1,2,4]triazol-5(4H)-one derivatives was designed and synthesized, and their in vivo anticonvulsant activities were evaluated using subcutaneous pentylenetetrazole (Sc-PTZ) and maximal electroshock (MES) tests. Compounds 3u, 4f...
3.
Jin Y, Dong N, Shimizu S, Li Y, Yao Y, Qiao H, et al.
Toxicol Appl Pharmacol
. 2025 Jan;
495:117234.
PMID: 39832567
The incidence rate and mortality rate of breast cancer remain high, and there is an urgent need for safe and effective drugs. The excellent biological activity of hesperidin (HE) is...
4.
Wang Y, Zhang J, Wu X, Huang L, Xiao W, Guo C
J Med Chem
. 2024 Dec;
68(1):18-48.
PMID: 39723587
PARP (poly-ADP ribose polymerase) has received widespread attention in cancer treatment. Research has shown that PARP plays a crucial role in DNA damage repair and has become a popular target...
5.
Wang Y, Xue P, Gao L, Wang X, Zhou S, Wu X, et al.
Int J Biol Macromol
. 2024 Dec;
287():138577.
PMID: 39657878
Cisplatin induced acute kidney injury (AKI) is clinically prevalent, with a complex pathogenesis and a lack of effective therapeutic drugs. Polydatin (Po) has excellent biological activity, but its low solubility...
6.
Zhou S, Yu Z, Yao W, Wang M, Yang Y, Qin J, et al.
Colloids Surf B Biointerfaces
. 2024 Dec;
247():114419.
PMID: 39626611
Ulcerative colitis is a recurring condition that causes inflammation and sores in the digestive system. Current clinical treatments for ulcerative colitis have limitations due to side effects and poor patient...
7.
Jiang T, Zhu F, Gao X, Wu X, Zhu W, Guo C
Colloids Surf B Biointerfaces
. 2024 Nov;
245:114343.
PMID: 39486374
Acute kidney injury (AKI) is a common clinical problem with no effective treatment. Excessive folic acid (FA) induced kidney tubular injury is characterized by oxidative stress and inflammation, and is...
8.
Zhai G, Wang Y, Han P, Xiao T, You J, Guo C, et al.
Int J Biol Macromol
. 2024 Oct;
281(Pt 2):135779.
PMID: 39419688
Marine polysaccharide-based biomaterials possess a range of excellent functions and properties, such as antiviral, antioxidant, immune regulation, and promoting cell migration, and are widely used in modern medicine. In this...
9.
Xu S, Wang Y, Han P, Yan S, You J, Guo C, et al.
Int J Biol Macromol
. 2024 Sep;
279(Pt 3):135270.
PMID: 39233162
Proper wound dressing is essential to facilitate skin wound healing, stop bleeding, and prevent infections. Herein, carboxymethyl chitosan (CMC) was crosslinked with oxidized tannic acid (OTA) to form an adhesive...
10.
Zhang C, Yang X, Wu L, Liu F, Dong K, Guo C, et al.
ACS Pharmacol Transl Sci
. 2024 May;
7(5):1426-1437.
PMID: 38751623
Protein tyrosine phosphatase 1B (PTP1B) and TC-PTP can function in a coordinated manner to regulate diverse biological processes including insulin and leptin signaling, T-cell activation, and tumor antigen presentation, which...