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Kehong Dong

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Articles 8
Citations 31
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Recent Articles
1.
Zhang C, Yang X, Wu L, Liu F, Dong K, Guo C, et al.
ACS Pharmacol Transl Sci . 2024 May; 7(5):1426-1437. PMID: 38751623
Protein tyrosine phosphatase 1B (PTP1B) and TC-PTP can function in a coordinated manner to regulate diverse biological processes including insulin and leptin signaling, T-cell activation, and tumor antigen presentation, which...
2.
Zhou S, Sun Y, Wang K, Gao X, Dong K, Wang J, et al.
Food Chem Toxicol . 2023 Dec; 184:114427. PMID: 38160781
Oxaliplatin (OXL) is a first-line drug for the treatment of colon cancer, with excellent efficacy. Intestinal toxicity is a common side effect of OXL, with unclear pathogenesis and a lack...
3.
Dong K, Sun Y, Gao X, Wang J, Wu X, Guo C
Colloids Surf B Biointerfaces . 2023 Nov; 233:113656. PMID: 37984191
Excessive acetaminophen (APAP) is the main cause of drug-induced acute liver failure, and the pathogenesis has not been elucidated and there is a lack of effective drugs. Hesperidin (Hes), a...
4.
Gao X, Yin Y, Liu S, Dong K, Wang J, Guo C
Int J Biol Macromol . 2023 Jun; 245:125541. PMID: 37355076
Fucoidan (FU) is a natural polymer from marine organisms, which has been widely studied and applied in drug delivery. In this study, FU nanoparticles loaded with proanthocyanidins (PCs) (FU/PCs NPs)...
5.
Liu S, Gao X, Yin Y, Wang J, Dong K, Shi D, et al.
Food Chem Toxicol . 2023 May; 177:113844. PMID: 37244599
Silk fibroin (SF) has excellent biocompatibility and biodegradability as a biomaterial. The purity and molecular weight distribution of silk fibroin peptide (SFP) make it more suitable for medical application. In...
6.
Dong K, Zhang M, Liu Y, Gao X, Wu X, Shi D, et al.
Mol Pharm . 2023 Jan; 20(2):1189-1201. PMID: 36647568
Excessive acetaminophen (APAP) induces excess reactive oxygen species (ROS), leading to liver damage. Pterostilbene (PTE) has excellent antioxidant and anti-inflammatory activities, but poor solubility limits its biological activity. In this...
7.
Gao X, Wang J, Wang Y, Liu S, Dong K, Wu J, et al.
Int J Biol Macromol . 2022 Nov; 223(Pt A):1083-1093. PMID: 36372101
Fucoidan (FU) is a natural sulfated polysaccharide with certain biological activity and has been shown to be an excellent nano-delivery material. In this study, ferulic acid (FA)-loaded FU nanoparticles (FA/FU...
8.
Liu S, Gao X, Wang Y, Wang J, Qi X, Dong K, et al.
Int J Pharm . 2022 Sep; 626:122161. PMID: 36058409
Silk fibroin (SF) is a natural polymeric biomaterial widely used in the preparation of drug delivery systems. Herein, silk fibroin peptide (SFP) was self-assembled into nanofibers, encapsulated a poorly water-soluble...