Xiaochen Wu
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Explore the profile of Xiaochen Wu including associated specialties, affiliations and a list of published articles.
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87
Citations
430
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Recent Articles
1.
Gao X, Jiang T, Wu X, Li Y, Xiao J, Long L, et al.
Int J Biol Macromol
. 2025 Mar;
:141976.
PMID: 40086544
Cervical cancer remains one of the leading causes of mortality among women, and immunotherapy targeting the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway holds promise for its treatment....
2.
Xu Y, An D, Zhang T, Wu X, Wang S, Shao J, et al.
Adv Mater
. 2025 Feb;
:e2418894.
PMID: 39988853
CGAS-STING agonists generally lead to hyperimmunity and systemic toxicity, hindering their immunotherapeutic outcomes. Herein, a mitochondrion-targeted nanoagonist (termed HABH) containing boron dipyrromethene (BODIPY)-derived type I photosensitizer (BDP) and Au nanoparticle-engineered...
3.
Liu Y, Ge X, Wu X, Guan L
ACS Omega
. 2025 Jan;
10(2):2222-2230.
PMID: 39866601
This study investigates the therapeutic potential of hyaluronic acid/proanthocyanidin (HA/PAC) nanoparticles in treating alkali-induced corneal burns. Alkali burns are common ocular emergencies that can lead to severe vision impairment if...
4.
Fu W, Zhao M, Ding S, Xin M, Yang K, Jiang L, et al.
Front Pharmacol
. 2025 Jan;
15():1519869.
PMID: 39845789
Background: Anticoagulants are the primary means for the treatment and prevention of venous thromboembolism (VTE), but their clinical standardized application still remains controversial. The present study intends to comprehensively compare...
5.
Wang Y, Zhang J, Wu X, Huang L, Xiao W, Guo C
J Med Chem
. 2024 Dec;
68(1):18-48.
PMID: 39723587
PARP (poly-ADP ribose polymerase) has received widespread attention in cancer treatment. Research has shown that PARP plays a crucial role in DNA damage repair and has become a popular target...
6.
Wang Y, Xue P, Gao L, Wang X, Zhou S, Wu X, et al.
Int J Biol Macromol
. 2024 Dec;
287():138577.
PMID: 39657878
Cisplatin induced acute kidney injury (AKI) is clinically prevalent, with a complex pathogenesis and a lack of effective therapeutic drugs. Polydatin (Po) has excellent biological activity, but its low solubility...
7.
Zhou S, Yu Z, Yao W, Wang M, Yang Y, Qin J, et al.
Colloids Surf B Biointerfaces
. 2024 Dec;
247():114419.
PMID: 39626611
Ulcerative colitis is a recurring condition that causes inflammation and sores in the digestive system. Current clinical treatments for ulcerative colitis have limitations due to side effects and poor patient...
8.
Wang J, Wu X, Zhang W, Bi X, Wang Y, Yu L, et al.
Cancer Nurs
. 2024 Nov;
PMID: 39495041
Background: Symptom distress and functional impairments in children with leukemia directly affect their quality of life. Objectives: To identify subgroups of symptom distress and functional impairments in Chinese children with...
9.
Jiang T, Zhu F, Gao X, Wu X, Zhu W, Guo C
Colloids Surf B Biointerfaces
. 2024 Nov;
245:114343.
PMID: 39486374
Acute kidney injury (AKI) is a common clinical problem with no effective treatment. Excessive folic acid (FA) induced kidney tubular injury is characterized by oxidative stress and inflammation, and is...
10.
Zhai G, Wang Y, Han P, Xiao T, You J, Guo C, et al.
Int J Biol Macromol
. 2024 Oct;
281(Pt 2):135779.
PMID: 39419688
Marine polysaccharide-based biomaterials possess a range of excellent functions and properties, such as antiviral, antioxidant, immune regulation, and promoting cell migration, and are widely used in modern medicine. In this...