Christopher Terranova
Overview
Explore the profile of Christopher Terranova including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
591
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0
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Recent Articles
1.
Lee H, Saw A, Morris V, Napolitano S, Bristow C, Srinivasan S, et al.
Clin Cancer Res
. 2024 Sep;
30(22):5166-5179.
PMID: 39269307
Purpose: BRAFV600E-mutated colorectal cancer exhibits a strong correlation with DNA hypermethylation, suggesting that this subgroup of tumors presents unique epigenomic phenotypes. Nonetheless, 5-azacitidine, which inhibits DNA methyltransferase activity, is not...
2.
Li J, Lan Z, Liao W, Horner J, Xu X, Liu J, et al.
Nature
. 2023 Jun;
619(7970):632-639.
PMID: 37344599
Sex exerts a profound impact on cancer incidence, spectrum and outcomes, yet the molecular and genetic bases of such sex differences are ill-defined and presumptively ascribed to X-chromosome genes and...
3.
Rahman S, Lan X, Terranova C, El-Kholdi R, Yilmaz O, Cheng C
Methods Mol Biol
. 2023 Jun;
2650:77-88.
PMID: 37310625
The equilibrium between stem cell self-renewal and differentiation followed by proper lineage specification of progenitor cells is considered imperative for maintaining intestinal homeostasis. In the hierarchical model, intestinal differentiation is...
4.
Kochat V, Raman A, Landers S, Tang M, Schulz J, Terranova C, et al.
Acta Neuropathol
. 2021 Jul;
142(3):565-590.
PMID: 34283254
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that frequently harbor genetic alterations in polycomb repressor complex 2 (PRC2) components-SUZ12 and EED. Here, we show that PRC2 loss...
5.
Orouji E, Raman A, Singh A, Sorokin A, Arslan E, Ghosh A, et al.
Gut
. 2021 Jun;
71(5):938-949.
PMID: 34059508
Objective: Enhancer aberrations are beginning to emerge as a key epigenetic feature of colorectal cancers (CRC), however, a comprehensive knowledge of chromatin state patterns in tumour progression, heterogeneity of these...
6.
Maitituoheti M, Keung E, Tang M, Yan L, Alam H, Han G, et al.
Cell Rep
. 2020 Oct;
33(3):108293.
PMID: 33086062
Histone methyltransferase KMT2D harbors frequent loss-of-function somatic point mutations in several tumor types, including melanoma. Here, we identify KMT2D as a potent tumor suppressor in melanoma through an in vivo...
7.
Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, et al.
Nat Commun
. 2020 Sep;
11(1):4766.
PMID: 32958778
Germline telomere maintenance defects are associated with an increased incidence of inflammatory diseases in humans, yet whether and how telomere dysfunction causes inflammation are not known. Here, we show that...
8.
Cheng C, Biton M, Haber A, Gunduz N, Eng G, Gaynor L, et al.
Cell
. 2019 Aug;
178(5):1115-1131.e15.
PMID: 31442404
Little is known about how metabolites couple tissue-specific stem cell function with physiology. Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the...
9.
Adhikary S, Chakravarti D, Terranova C, Sengupta I, Maitituoheti M, Dasgupta A, et al.
Nat Commun
. 2019 Mar;
10(1):1398.
PMID: 30923315
The roles of Plant Homeodomain (PHD) fingers in catalysis of histone modifications are unknown. We demonstrated that the PHD finger of Ubiquitin Protein Ligase E3 Component N-Recognin7 (UBR7) harbors E3...
10.
Deribe Y, Sun Y, Terranova C, Khan F, Martinez-Ledesma J, Gay J, et al.
Nat Med
. 2018 Aug;
24(10):1627.
PMID: 30104769
In the version of this article originally published, information regarding several funding sources was omitted from the Acknowledgements section. The following sentences should have been included: "This work was supported...