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Christopher M Johnson

Explore the profile of Christopher M Johnson including associated specialties, affiliations and a list of published articles. Areas
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Articles 131
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Recent Articles
11.
Wu Y, Cui N, Xing H, Zhong W, Arrowood C, Johnson C, et al.
J Cell Physiol . 2021 Jun; 236(12):8082-8098. PMID: 34077559
Rett syndrome (RTT) is a neurodevelopmental disorder caused mostly by mutations in the MECP2 gene. RTT patients show periodical hypoventilation attacks. The breathing disorder contributing to the high incidence of...
12.
Johnson C
Methods Mol Biol . 2021 Apr; 2263:135-159. PMID: 33877596
Calorimetry is a classical biophysical method that by definition measures heat. In isothermal titration calorimetry (ITC), the heat is the result of titrating interacting components together and allows direct determination...
13.
Segawa T, Johnson C, Berntsson R, Dunny G
Mol Microbiol . 2021 Apr; 116(2):459-469. PMID: 33817866
Enterococcal pheromone-inducible plasmids encode a predicted OppA-family secreted lipoprotein. In the case of plasmid pCF10, the protein is PrgZ, which enhances the mating response to cCF10 pheromone. OppA proteins generally...
14.
Zeng J, Santos A, Mukadam A, Osswald M, Jacques D, Dickson C, et al.
Nat Struct Mol Biol . 2021 Feb; 28(3):278-289. PMID: 33633400
Trim-Away is a recently developed technology that exploits off-the-shelf antibodies and the RING E3 ligase and cytosolic antibody receptor TRIM21 to carry out rapid protein depletion. How TRIM21 is catalytically...
15.
Xing H, Cui N, Johnson C, Faisthalab Z, Jiang C
J Cell Physiol . 2020 Nov; 236(5):3615-3628. PMID: 33169374
Rett syndrome (RTT) is a neurodevelopmental disease caused mostly by mutations in the MECP2 gene. People with RTT show breathing dysfunction attributable to the high rate of sudden death. Previous...
16.
Johnson C, Cui N, Xing H, Wu Y, Jiang C
Neuropharmacology . 2020 Jul; 176:108214. PMID: 32622786
Rett Syndrome (RTT) is an X-linked neurodevelopmental disorder caused mainly by mutations in the MECP2 gene. One of the major RTT features is breathing dysfunction characterized by periodic hypo- and...
17.
Ohashi Y, Tremel S, Masson G, McGinney L, Boulanger J, Rostislavleva K, et al.
Elife . 2020 Jul; 9. PMID: 32602837
The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic sorting, phagocytosis, anabolic responses and cell division. VPS34 forms various complexes that help adapt it to specific pathways, with complexes...
18.
Kamath S, Scheiblhofer S, Johnson C, Machado Y, McLean T, Taki A, et al.
Allergy . 2020 May; 75(11):2909-2919. PMID: 32436591
Background: Tropomyosins are highly conserved proteins, an attribute that forms the molecular basis for their IgE antibody cross-reactivity. Despite sequence similarities, their allergenicity varies greatly between ingested and inhaled invertebrate...
19.
Ochi T, Quarantotti V, Lin H, Jullien J, E Silva I, Boselli F, et al.
Structure . 2020 May; 28(6):674-689.e11. PMID: 32375023
Centrioles are cylindrical assemblies whose peripheral microtubule array displays a 9-fold rotational symmetry that is established by the scaffolding protein SAS6. Centriole symmetry can be broken by centriole-associated structures, such...
20.
Johnson C, Fenn J, Brown A, Jung P
Phys Biol . 2020 May; 17(4):046004. PMID: 32369788
Cytoplasmic dynein is an important molecular motor involved in the transport of vesicular and macromolecular cargo along microtubules in cells, often in conjunction with kinesin motors. Dynein is larger and...