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Christopher M Johnson

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Articles 131
Citations 3648
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Recent Articles
21.
Wilson T, Clare S, Mikulin J, Johnson C, Harcourt K, Lyons P, et al.
Immunology . 2019 Dec; 159(4):393-403. PMID: 31880316
Signalling lymphocyte activation molecule family member 9 (SLAMF9) is an orphan receptor of the CD2/SLAM family of leucocyte surface proteins. Examination of SLAMF9 expression and function indicates that SLAMF9 promotes...
22.
Heiby J, Goretzki B, Johnson C, Hellmich U, Neuweiler H
Nat Commun . 2019 Sep; 10(1):4378. PMID: 31558722
Web spiders connect silk proteins, so-called spidroins, into fibers of extraordinary toughness. The spidroin N-terminal domain (NTD) plays a pivotal role in this process: it polymerizes spidroins through a complex...
23.
Johnson C, Linzay C, Dassopoulos T
Curr Gastroenterol Rep . 2019 Sep; 21(10):52. PMID: 31486929
Purpose Of Review: Recent years have brought about several advances in the treatment of patients with ulcerative colitis (UC). Here, we discuss salient recommendations of recent treatment guidelines; review the...
24.
Baretic D, De Oliveira T, Niess M, Wan P, Pollard H, Johnson C, et al.
Prog Biophys Mol Biol . 2019 Jul; 147:4-16. PMID: 31255703
ATM, ATR and DNA-PKCs are key effectors of DNA Damage response and have been extensively linked to tumourigenesis and survival of cancer cells after radio/chemotherapy. Despite numerous efforts, the structures...
25.
Yadahalli S, Neira J, Johnson C, Sing Tan Y, Rowling P, Chattopadhyay A, et al.
Sci Rep . 2019 Jan; 9(1):693. PMID: 30679555
p53 is frequently mutated in human cancers. Its levels are tightly regulated by the E3 ubiquitin ligase MDM2. The complex between MDM2 and p53 is largely formed by the interaction...
26.
Nirwan N, Singh P, Mishra G, Johnson C, Szczelkun M, Inoue K, et al.
Nucleic Acids Res . 2018 Dec; 47(2):868-882. PMID: 30521042
McrBC is one of the three modification-dependent restriction enzymes encoded by the Escherichia coli K12 chromosome. Amongst restriction enzymes, McrBC and its close homologues are unique in employing the AAA+...
27.
Wu Y, Cui N, Xing H, Zhong W, Arrowood C, Johnson C, et al.
Neuroscience . 2018 Nov; 397:107-115. PMID: 30458221
People with Rett Syndrome (RTT), a neurodevelopmental disorder caused by mutations in the MECP2 gene, have breathing abnormalities manifested as periodical hypoventilation with compensatory hyperventilation, which are attributable to a...
28.
Mariani A, Bonfio C, Johnson C, Sutherland J
Biochemistry . 2018 Nov; 57(45):6382-6386. PMID: 30383375
Replication of nucleic acids in the absence of genetically encoded enzymes represents a critical process for the emergence of cellular life. Repeated separation of complementary RNA strands is required to...
29.
Johnson C, Dassopoulos T
Curr Gastroenterol Rep . 2018 Sep; 20(11):53. PMID: 30267281
Purpose Of Review: The increased use of biologic agents over the past two decades has led to a reappraisal of the role of the immunomodulators (thiopurines and methotrexate) in the...
30.
Johnson C, Anderson D, Brigger M
J Voice . 2018 Sep; 34(2):301.e1-301.e5. PMID: 30236538
Objectives: Prevalence data for pediatric dysphonia are sparse and primarily collected either in the community or within pediatric otolaryngology clinics. The objectives were to determine the prevalence of dysphonia in...