Christopher L Warren
Overview
Explore the profile of Christopher L Warren including associated specialties, affiliations and a list of published articles.
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17
Citations
866
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Recent Articles
1.
Helzer K, Ozers M, Meyer M, Benkusky N, Solodin N, Reese R, et al.
Mol Cell Biol
. 2018 Nov;
39(3).
PMID: 30455249
Posttranslational modifications are key regulators of protein function, providing cues that can alter protein interactions and cellular location. Phosphorylation of estrogen receptor α (ER) at serine 118 (pS118-ER) occurs in...
2.
Rajbhandari P, Ozers M, Solodin N, Warren C, Alarid E
J Biol Chem
. 2015 Apr;
290(22):13749-62.
PMID: 25866209
The transcriptional activity of estrogen receptor α (ERα), the key driver of breast cancer proliferation, is enhanced by multiple cellular interactions, including phosphorylation-dependent interaction with Pin1, a proline isomerase, which...
3.
Duellman T, Warren C, Matsumura J, Yang J
J Vasc Surg
. 2014 May;
60(3):613-21.e3.
PMID: 24801553
Background: The natural history of abdominal aortic aneurysms (AAAs) suggests that some remain slow in growth rate whereas many develop a more accelerated growth rate and reach a threshold for...
4.
Ding L, Zhao Y, Warren C, Sullivan R, Eliceiri K, Shull J
BMC Cancer
. 2013 Dec;
13:573.
PMID: 24304664
Background: We are using ACI and BN rats, which differ markedly in their susceptibility to 17β-estradiol (E2)-induced mammary cancer, to identify genetic variants and environmental factors that determine mammary cancer...
5.
Schaffer B, Leland-Wavrin K, Kurz S, Colletti J, Seiler N, Warren C, et al.
Cancer Prev Res (Phila)
. 2012 Nov;
6(1):59-69.
PMID: 23151807
The ACI rat model of 17β-estradiol (E2)-induced mammary cancer has gained wide use in the study of breast cancer etiology, prevention, and genetics. Emca8, a QTL that determines susceptibility to...
6.
Duellman T, Warren C, Peissig P, Wynn M, Yang J
Circ Cardiovasc Genet
. 2012 Sep;
5(5):529-37.
PMID: 22942228
Background: Degradation of extracellular matrix support in the large abdominal arteries contribute to abnormal dilation of aorta, leading to abdominal aortic aneurysms, and matrix metalloproteinase-9 (MMP-9) is the predominant enzyme...
7.
Warren C, Zhao J, Glass K, Rishi V, Ansari A, Vinson C
Lab Chip
. 2011 Dec;
12(2):376-80.
PMID: 22139143
We synthesized customized double-stranded DNA microarrays including methyl-5-cytosine at CpG dinucleotides and produced all 163,555 possible 8-mers (un-, hemi-, and di-methylated) to gain insight into how methylation affects transcription factor...
8.
Muller P, Park S, Shor E, Huebert D, Warren C, Ansari A, et al.
Genes Dev
. 2010 Jul;
24(13):1418-33.
PMID: 20595233
The origin recognition complex (ORC) binds to the specific positions on chromosomes that serve as DNA replication origins. Although ORC is conserved from yeast to humans, the DNA sequence elements...
9.
Carlson C, Warren C, Hauschild K, Ozers M, Qadir N, Bhimsaria D, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(10):4544-9.
PMID: 20176964
Evaluating the specificity spectra of DNA binding molecules is a nontrivial challenge that hinders the ability to decipher gene regulatory networks or engineer molecules that act on genomes. Here we...
10.
Shor E, Warren C, Tietjen J, Hou Z, Muller U, Alborelli I, et al.
PLoS Genet
. 2009 Dec;
5(12):e1000755.
PMID: 19997491
The origin recognition complex (ORC) marks chromosomal sites as replication origins and is essential for replication initiation. In yeast, ORC also binds to DNA elements called silencers, where its primary...