Alpha 2.0
Login Register
» Authors » Christopher L Warren

Christopher L Warren

Explore the profile of Christopher L Warren including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 866
Followers 0
Related Specialties
Cell Biology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Aseem Z Ansari
Clayton D Carlson
Erika Shor
James D Shull
Mary Szatkowski Ozers
Elaine T Alarid
Catherine A Fox
Peter B Dervan
Tyler Duellman
Mary S Ozers
Published In
Proc Natl Acad Sci U S A
Mol Cell
Nucleic Acids Res
PLoS Genet
Circ Cardiovasc Genet
Affiliations
Soon will be listed here.
Recent Articles
11.
Determining DNA sequence specificity of natural and artificial transcription factors by cognate site identifier analysis
Ozers M, Warren C, Ansari A
Methods Mol Biol . 2009 Jun; 544:637-53. PMID: 19488729
Artificial transcription factors (ATFs) are designed to mimic natural transcription factors in the control of gene expression and are comprised of domains for DNA binding and gene regulation. ATF domains...
12.
Cognate Site Identifier analysis reveals novel binding properties of the Sex Inducer homeodomain proteins of Cryptococcus neoformans
Stanton B, Giles S, Kruzel E, Warren C, Ansari A, Hull C
Mol Microbiol . 2009 Jun; 72(6):1334-47. PMID: 19486297
Homeodomain proteins function in fungi to specify cell types and control sexual development. In the meningoencephalitis-causing fungal pathogen Cryptococcus neoformans, sexual development leads to the production of spores (suspected infectious...
13.
A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters
Badis G, Chan E, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, et al.
Mol Cell . 2008 Dec; 32(6):878-87. PMID: 19111667
The sequence specificity of DNA-binding proteins is the primary mechanism by which the cell recognizes genomic features. Here, we describe systematic determination of yeast transcription factor DNA-binding specificities. We obtained...
14.
CSI-Tree: a regression tree approach for modeling binding properties of DNA-binding molecules based on cognate site identification (CSI) data
Keles S, Warren C, Carlson C, Ansari A
Nucleic Acids Res . 2008 Apr; 36(10):3171-84. PMID: 18411210
The identification and characterization of binding sites of DNA-binding molecules, including transcription factors (TFs), is a critical problem at the interface of chemistry, biology and molecular medicine. The Cognate Site...
15.
Quantitative microarray profiling of DNA-binding molecules
Puckett J, Muzikar K, Tietjen J, Warren C, Ansari A, Dervan P
J Am Chem Soc . 2007 Sep; 129(40):12310-9. PMID: 17880081
A high-throughput Cognate Site Identity (CSI) microarray platform interrogating all 524 800 10-base pair variable sites is correlated to quantitative DNase I footprinting data of DNA binding pyrrole-imidazole polyamides. An...
16.
Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase
Steinmetz E, Warren C, Kuehner J, Panbehi B, Ansari A, Brow D
Mol Cell . 2006 Dec; 24(5):735-746. PMID: 17157256
Functional engagement of RNA polymerase II (Pol II) with eukaryotic chromosomes is a fundamental and highly regulated biological process. Here we present a high-resolution map of Pol II occupancy across...
17.
Defining the sequence-recognition profile of DNA-binding molecules
Warren C, Kratochvil N, Hauschild K, Foister S, Brezinski M, Dervan P, et al.
Proc Natl Acad Sci U S A . 2006 Jan; 103(4):867-72. PMID: 16418267
Determining the sequence-recognition properties of DNA-binding proteins and small molecules remains a major challenge. To address this need, we have developed a high-throughput approach that provides a comprehensive profile of...