Christina C Luo
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Explore the profile of Christina C Luo including associated specialties, affiliations and a list of published articles.
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19
Citations
1836
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Recent Articles
11.
Jerby-Arnon L, Neftel C, Shore M, Weisman H, Mathewson N, McBride M, et al.
Nat Med
. 2021 Jan;
27(2):289-300.
PMID: 33495604
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18-SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer-immune interplay in SyS using an...
12.
Powell R, Weiss S, Fox A, Liu X, Itri V, Jiang X, et al.
J Virol
. 2020 Jun;
94(17).
PMID: 32554699
The HIV vaccine field now recognizes the potential importance of generating polyfunctional antibodies (Abs). The only clinical HIV vaccine trial to date to show significant efficacy (RV144) found that reduced...
13.
Karaayvaz M, Cristea S, Gillespie S, Patel A, Mylvaganam R, Luo C, et al.
Nat Commun
. 2018 Sep;
9(1):3588.
PMID: 30181541
Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by extensive intratumoral heterogeneity. To investigate the underlying biology, we conducted single-cell RNA-sequencing (scRNA-seq) of >1500 cells from six primary TNBC....
14.
Filbin M, Tirosh I, Hovestadt V, Shaw M, Escalante L, Mathewson N, et al.
Science
. 2018 Apr;
360(6386):331-335.
PMID: 29674595
Gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) arise primarily in the midline of the central nervous system of young children, suggesting a cooperation between genetics and cellular context in tumorigenesis....
15.
Kara E, Marks J, Fan Z, Klickstein J, Roe A, Krogh K, et al.
J Biol Chem
. 2017 Jul;
292(36):14720-14729.
PMID: 28684412
Apolipoprotein E (apoE) has an important role in the pathogenesis of Alzheimer's disease with its three isoforms having distinct effects on disease risk. Here, we assessed the conformational differences between...
16.
Venteicher A, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin M, et al.
Science
. 2017 Apr;
355(6332).
PMID: 28360267
Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as the composition of the tumor microenvironment (TME). We dissected these influences in isocitrate dehydrogenase (IDH)-mutant...
17.
Tirosh I, Venteicher A, Hebert C, Escalante L, Patel A, Yizhak K, et al.
Nature
. 2016 Nov;
539(7628):309-313.
PMID: 27806376
Although human tumours are shaped by the genetic evolution of cancer cells, evidence also suggests that they display hierarchies related to developmental pathways and epigenetic programs in which cancer stem...
18.
Deshpande M, Feiger Z, Shilton A, Luo C, Silverman E, Rodal A
Mol Biol Cell
. 2016 Aug;
27(19):2898-910.
PMID: 27535427
TAR DNA-binding protein 43 (TDP-43) is genetically and functionally linked to amyotrophic lateral sclerosis (ALS) and regulates transcription, splicing, and transport of thousands of RNA targets that function in diverse...
19.
Moore F, Garcia E, Lobbardi R, Jain E, Tang Q, Moore J, et al.
J Exp Med
. 2016 May;
213(6):979-92.
PMID: 27139488
Hematopoiesis culminates in the production of functionally heterogeneous blood cell types. In zebrafish, the lack of cell surface antibodies has compelled researchers to use fluorescent transgenic reporter lines to label...