Christian Beisel
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Explore the profile of Christian Beisel including associated specialties, affiliations and a list of published articles.
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88
Citations
5200
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Recent Articles
1.
Wegmann R, Bonilla X, Casanova R, Chevrier S, Coelho R, Esposito C, et al.
Nat Commun
. 2024 Oct;
15(1):9402.
PMID: 39477946
Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug...
2.
Chan T, Ginders J, Kuhlmeier E, Meli M, Bonzli E, Meili T, et al.
Viruses
. 2024 Apr;
16(4).
PMID: 38675864
Many different animal species are susceptible to SARS-CoV-2, including a few Canidae (domestic dog and raccoon dog). So far, only experimental evidence is available concerning SARS-CoV-2 infections in red foxes...
3.
Hamelin B, Obradovic M, Sethi A, Kloc M, Munst S, Beisel C, et al.
J Mammary Gland Biol Neoplasia
. 2023 Dec;
28(1):26.
PMID: 38066300
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps, referred to as the metastatic cascade, and give...
4.
Dondi A, Lischetti U, Jacob F, Singer F, Borgsmuller N, Coelho R, et al.
Nat Commun
. 2023 Nov;
14(1):7780.
PMID: 38012143
Understanding the complex background of cancer requires genotype-phenotype information in single-cell resolution. Here, we perform long-read single-cell RNA sequencing (scRNA-seq) on clinical samples from three ovarian cancer patients presenting with...
5.
Lischetti U, Tastanova A, Singer F, Grob L, Carrara M, Cheng P, et al.
Commun Biol
. 2023 Aug;
6(1):830.
PMID: 37563418
Multi-omics profiling by CITE-seq bridges the RNA-protein gap in single-cell analysis but has been largely applied to liquid biopsies. Applying CITE-seq to clinically relevant solid biopsies to characterize healthy tissue...
6.
Wiberg R, Brand J, Viktorin G, Mitchell J, Beisel C, Scharer L
G3 (Bethesda)
. 2023 Jul;
13(9).
PMID: 37398989
The free-living, simultaneously hermaphroditic flatworms of the genus Macrostomum are increasingly used as model systems in various contexts. In particular, Macrostomum lignano, the only species of this group with a...
7.
Goig G, Menardo F, Salaam-Dreyer Z, Dippenaar A, Streicher E, Daniels J, et al.
Lancet Microbe
. 2023 Jun;
4(7):e506-e515.
PMID: 37295446
Background: Experimental data show that drug-resistance-conferring mutations are often associated with a decrease in the replicative fitness of bacteria in vitro, and that this fitness cost can be mitigated by...
8.
Grob L, Bertolini A, Carrara M, Lischetti U, Tastanova A, Beisel C, et al.
Bioinformatics
. 2023 May;
39(5).
PMID: 37220897
Summary: Recently, CITE-seq emerged as a multimodal single-cell technology capturing gene expression and surface protein information from the same single cells, which allows unprecedented insights into disease mechanisms and heterogeneity,...
9.
Loiseau C, Windels E, Gygli S, Jugheli L, Maghradze N, Brites D, et al.
Nat Commun
. 2023 Apr;
14(1):1988.
PMID: 37031225
Multidrug-resistant tuberculosis (MDR-TB) is among the most frequent causes of death due to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical hotspots with up to 40%...
10.
Kuhlmeier E, Chan T, Valenzuela Agui C, Willi B, Wolfensberger A, Beisel C, et al.
Viruses
. 2023 Jan;
15(1).
PMID: 36680285
In human beings, there are five reported variants of concern of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). However, in contrast to human beings, descriptions of infections of animals...