Mitchell P Levesque
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Explore the profile of Mitchell P Levesque including associated specialties, affiliations and a list of published articles.
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179
Citations
6437
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Recent Articles
1.
Cohen Shvefel S, Pai J, Cao Y, Pal L, Bartok O, Levy R, et al.
Cancer Discov
. 2025 Jan;
OF1-OF25.
PMID: 39873477
In this study, we find that Mif expression is associated with tumor growth and aggressiveness, specifically in tumors with low heterogeneity. These findings could facilitate the development of new strategies...
2.
Rutsche D, Nanni M, Cheng P, Caflisch N, Tastanova A, Jenni C, et al.
Small Methods
. 2025 Jan;
e2401588.
PMID: 39871784
The bioengineering of vascular networks is pivotal to create complex tissues and organs for regenerative medicine applications. However, bioengineered tissues comprising an arterial and venous plexus alongside a lymphatic capillary...
3.
Cereghetti A, Turko P, Cheng P, Benke S, Al Hrout A, Dzung A, et al.
JID Innov
. 2025 Jan;
5(2):100319.
PMID: 39867570
In cutaneous melanoma, epigenetic dysregulation is implicated in drug resistance and tumor immune escape. However, the epigenetic mechanisms that influence immune escape remain poorly understood. To elucidate how epigenetic dysregulation...
4.
Cohen Shvefel S, Pai J, Cao Y, Pal L, Bartok O, Levy R, et al.
Cancer Discov
. 2024 Dec;
PMID: 39715301
Low intra-tumor heterogeneity (ITH) correlates with increased patient survival and immunotherapy response. However, even highly homogeneous tumors are variably aggressive, and the immunological factors impacting aggressiveness remain understudied. Here, we...
5.
Loos B, Salas-Bastos A, Nordin A, Debbache J, Stierli S, Cheng P, et al.
Cell Death Dis
. 2024 Dec;
15(12):925.
PMID: 39709491
The TGFβ signaling pathway is known for its pleiotropic functions in a plethora of biological processes. In melanoma, TGFβ signaling promotes invasiveness and metastasis formation. However, its involvement in the...
6.
Wegmann R, Bonilla X, Casanova R, Chevrier S, Coelho R, Esposito C, et al.
Nat Commun
. 2024 Oct;
15(1):9402.
PMID: 39477946
Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug...
7.
Nordmann T, Anderton H, Hasegawa A, Schweizer L, Zhang P, Stadler P, et al.
Nature
. 2024 Oct;
635(8040):1001-1009.
PMID: 39415009
Toxic epidermal necrolysis (TEN) is a fatal drug-induced skin reaction triggered by common medications and is an emerging public health issue. Patients with TEN undergo severe and sudden epidermal detachment...
8.
Birkenmaier I, Maul L, Oyanguren I, Sorbe C, Frohlich F, Schlapbach C, et al.
Arch Dermatol Res
. 2024 Oct;
316(9):654.
PMID: 39352439
Real-world data on anatomically localized psoriasis and its response to systemic therapy across different age-groups and sexes is limited. This study aimed to evaluate the severity and distribution of psoriasis...
9.
Knoch C, Baghin V, Turko P, Winkelbeiner N, Staeger R, Wei K, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273670
Lichen planus (LP) is a highly prevalent inflammatory skin disease. While various clinical subtypes have been defined, detailed comparisons of these variants are lacking. This study aimed to elucidate differences...
10.
Dimitriou F, Cheng P, Saltari A, Schaper-Gerhardt K, Staeger R, Haunerdinger V, et al.
Nat Cancer
. 2024 Aug;
5(9):1390-1408.
PMID: 39210005
Immune checkpoint inhibitors are standard-of-care for the treatment of advanced melanoma, but their use is limited by immune-related adverse events. Proteomic analyses and multiplex cytokine and chemokine assays from serum...