Cheng-Wei T Chang
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Explore the profile of Cheng-Wei T Chang including associated specialties, affiliations and a list of published articles.
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20
Citations
191
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Recent Articles
1.
Poudyal N, Subedi Y, Shakespear M, Grilley M, Takemoto J, Chang C
Bioorg Med Chem
. 2024 Oct;
114:117947.
PMID: 39418748
The World Health Organization (WHO) recognizes Candida albicans and Cryptococcus neoformans as the critical priority fungal pathogens for which therapeutic solutions are needed. Azole-based antifungal agents, including triazoles, diazoles, and...
2.
Liao T, Chen C, Lin C, Chang C, Takemoto J, Lin Y
J Anim Physiol Anim Nutr (Berl)
. 2023 Aug;
107(6):1368-1375.
PMID: 37539819
Weaning is a critical period in raising pigs. Novel animal feed additives that promote gut health and regulate immune function of piglets without antibiotics are needed. In this study, we...
3.
Chang C, Poudyal N, Verdugo D, Pena F, Stehberg J, Retamal M
Biomolecules
. 2023 Mar;
13(3).
PMID: 36979346
Background: Connexins (Cxs) are proteins that help cells to communicate with the extracellular media and with the cytoplasm of neighboring cells. Despite their importance in several human physiological and pathological...
4.
Takemoto J, Altenberg G, Poudyal N, Subedi Y, Chang C
Front Microbiol
. 2022 Oct;
13:1000199.
PMID: 36212866
Widely-used -derived antibacterial aminoglycosides have encountered challenges because of antibiotic resistance and toxicity. Today, they are largely relegated to medicinal topical applications. However, chemical modification to amphiphilic aminoglycosides can revive...
5.
Lin Y, Takemoto J, Chang C, Peng C
Biochem Biophys Res Commun
. 2022 Jun;
619:56-61.
PMID: 35738065
Heme oxygenase-1 (HO-1) expression promotes osteogenesis, but the mechanisms remain unclear and therapeutic strategies using it to target bone disorders such as osteoporosis have not progressed. Mesobiliverdin IXα is a...
6.
Natha C, Vemulapalli V, Fiori M, Chang C, Altenberg G
Biochim Biophys Acta Mol Basis Dis
. 2021 Mar;
1867(6):166115.
PMID: 33711451
Connexins are membrane proteins involved directly in cell-to-cell communication through the formation of gap-junctional channels. These channels result from the head-to-head docking of two hemichannels, one from each of two...
7.
Chang C, Takemoto J, Chang P, AlFindee M, Lin Y
Front Vet Sci
. 2021 Feb;
7:586813.
PMID: 33553275
Gut inflammatory bowel diseases (IBDs) links to animal medicinal feed and antibiotic-resistance are fueling major economic impacts in the agricultural livestock industry. New animal feeds that promote livestock gut health...
8.
Subedi Y, Altenberg G, Chang C
Future Med Chem
. 2021 Jan;
13(4):379-392.
PMID: 33399487
Gap-junction channels formed by two connexin hemichannels play diverse and pivotal roles in intercellular communication and regulation. Normally hemichannels at the plasma membrane participate in autocrine and paracrine signaling, but...
9.
Subedi Y, Kjellgren A, Roberts P, Montgomery H, Thackeray N, Fiori M, et al.
Eur J Med Chem
. 2020 Jul;
203:112602.
PMID: 32679454
Gap junction channels formed by the association of connexin hemichannels play a crucial role in intercellular communication. Connexin 43 (Cx43) is expressed in a variety of tissues and organs, including...
10.
AlFindee M, Subedi Y, Grilley M, Takemoto J, Chang C
Molecules
. 2019 May;
24(10).
PMID: 31100822
Amphiphilic kanamycins derived from the classic antibiotic kanamycin have attracted interest due to their novel bioactivities beyond inhibition of bacteria. In this study, the recently described 4″,6″-diaryl amphiphilic kanamycins reported...