Charles R Vanderburg
Overview
Explore the profile of Charles R Vanderburg including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
3358
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Recent Articles
1.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7994):E11.
PMID: 38110579
No abstract available.
2.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7993):101-109.
PMID: 38093010
Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed. However, missing from these...
3.
Chen C, Newman L, Stark A, Bond K, Zhang D, Nardone S, et al.
Nat Neurosci
. 2023 Nov;
26(11):1929-1941.
PMID: 37919612
In addition to its motor functions, the cerebellum is involved in emotional regulation, anxiety and affect. We found that suppressing the firing of cerebellar Purkinje cells (PCs) rapidly excites forebrain...
4.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
bioRxiv
. 2023 Apr;
PMID: 37066158
Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed. Missing from these measurements,...
5.
Frydman G, Ellett F, Jorgensen J, Marand A, Zukerberg L, Selig M, et al.
Front Immunol
. 2023 Mar;
14:1083339.
PMID: 36936945
Megakaryocytes (MKs) are precursors to platelets, the second most abundant cells in the peripheral circulation. However, while platelets are known to participate in immune responses and play significant functions during...
6.
Halvorsen S, Benita Y, Hopton M, Hoppe B, Gunnlaugsson H, Korgaonkar P, et al.
Am J Pathol
. 2023 Feb;
193(5):532-547.
PMID: 36804377
Chordoma is a rare malignant tumor demonstrating notochordal differentiation. It is dependent on brachyury (TBXT), a hallmark notochordal gene and transcription factor, and shares histologic features and the same anatomic...
7.
Cai W, Srivastava P, Feng D, Lin Y, Vanderburg C, Xu Y, et al.
Mol Neurodegener
. 2022 Feb;
17(1):16.
PMID: 35197079
Background: Epidemiological studies suggest a link between the melanoma-related pigmentation gene melanocortin 1 receptor (MC1R) and risk of Parkinson's disease (PD). We previously showed that MC1R signaling can facilitate nigrostriatal...
8.
Biancalani T, Scalia G, Buffoni L, Avasthi R, Lu Z, Sanger A, et al.
Nat Methods
. 2021 Oct;
18(11):1352-1362.
PMID: 34711971
Charting an organs' biological atlas requires us to spatially resolve the entire single-cell transcriptome, and to relate such cellular features to the anatomical scale. Single-cell and single-nucleus RNA-seq (sc/snRNA-seq) can...
9.
Yao Z, Liu H, Xie F, Fischer S, Adkins R, Aldridge A, et al.
Nature
. 2021 Oct;
598(7879):103-110.
PMID: 34616066
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased samples of the diverse cell types in the brain. With the proliferation of multi-omics datasets, a major challenge is to...
10.
Frydman G, Ellett F, Van Cott E, Hayden D, Majmudar M, Vanderburg C, et al.
Crit Care Explor
. 2020 Mar;
1(8):e0024.
PMID: 32166266
Design: First-in-human, 91-patient, single-center retrospective pilot study. Setting: Emergency room. Patients: Adult patients admitted into the emergency department, which received any clinician-ordered coagulation test requiring a 3.2% buffered sodium citrate...