Charles R Vanderburg
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Explore the profile of Charles R Vanderburg including associated specialties, affiliations and a list of published articles.
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43
Citations
3358
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Recent Articles
11.
Frydman G, Tessier S, Wong K, Vanderburg C, Fox J, Toner M, et al.
Sci Rep
. 2020 Mar;
10(1):4621.
PMID: 32165642
Histones are typically located within the intracellular compartment, and more specifically, within the nucleus. When histones are located within the extracellular compartment, they change roles and become damage-associated molecular patterns...
12.
Rodriques S, Stickels R, Goeva A, Martin C, Murray E, Vanderburg C, et al.
Science
. 2019 Mar;
363(6434):1463-1467.
PMID: 30923225
Spatial positions of cells in tissues strongly influence function, yet a high-throughput, genome-wide readout of gene expression with cellular resolution is lacking. We developed Slide-seq, a method for transferring RNA...
13.
Strunz M, Jarrell J, Cohen D, Rosin E, Vanderburg C, Huang X
J Alzheimers Dis
. 2019 Mar;
68(2):695-710.
PMID: 30883351
Alzheimer's disease (AD) is an age-related progressive form of dementia that features neuronal loss, intracellular tau, and extracellular amyloid-β (Aβ) protein deposition. Neurodegeneration is accompanied by neuroinflammation mainly involving microglia,...
14.
Eftekharzadeh B, Daigle J, Kapinos L, Coyne A, Schiantarelli J, Carlomagno Y, et al.
Neuron
. 2019 Jan;
101(2):349.
PMID: 30653936
No abstract available.
15.
Eftekharzadeh B, Daigle J, Kapinos L, Coyne A, Schiantarelli J, Carlomagno Y, et al.
Neuron
. 2018 Sep;
99(5):925-940.e7.
PMID: 30189209
Tau is the major constituent of neurofibrillary tangles in Alzheimer's disease (AD), but the mechanism underlying tau-associated neural damage remains unclear. Here, we show that tau can directly interact with...
16.
Jin M, ONuallain B, Hong W, Boyd J, Lagomarsino V, OMalley T, et al.
Nat Commun
. 2018 Jul;
9(1):2676.
PMID: 29992960
Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer's disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As...
17.
Vanderburg C, Davis D, Diamond R, Kao P, Delalle I
Transl Neurosci
. 2018 Apr;
1(1):55-58.
PMID: 29662700
The silencing of actin capping protein β2, Capzb2, by RNAi in developing cultured neurons results in short, dystrophic neurites reminiscent of cytoskeletal changes seen in diverse neurodegenerative diseases, including Alzheimer's...
18.
Marquie M, Verwer E, Meltzer A, Kim S, Aguero C, Gonzalez J, et al.
Acta Neuropathol Commun
. 2017 Oct;
5(1):75.
PMID: 29047416
[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer's disease (AD). PET studies have shown increased tracer retention in patients clinically...
19.
DiVincenzo M, Frydman G, Kowaleski M, Vanderburg C, Lai B, Oura T, et al.
Vet Pathol
. 2017 Jun;
54(5):828-831.
PMID: 28651457
Metallosis is the accumulation of metallic debris in soft tissues resulting from wear following total joint replacement. A dog was evaluated for lameness 4 years after total hip arthroplasty using...
20.
Frydman G, Marini R, Bakthavatchalu V, Biddle K, Muthupalani S, Vanderburg C, et al.
Comp Med
. 2017 Apr;
67(2):165-175.
PMID: 28381317
Metal alloys are frequently used as implant materials in veterinary medicine. Recent studies suggest that many alloys induce both local and systemic inflammatory responses. In this study, 37 rhesus macaques...