Charles Decraene
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Explore the profile of Charles Decraene including associated specialties, affiliations and a list of published articles.
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31
Citations
811
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Recent Articles
1.
Brule B, Alcala-Vida R, Penaud N, Scuto J, Mounier C, Seguin J, et al.
Nat Commun
. 2025 Feb;
16(1):1550.
PMID: 39934111
Loss of epigenetic information during physiological aging compromises cellular identity, leading to de-repression of developmental genes. Here, we assessed the epigenomic landscape of vulnerable neurons in two reference mouse models...
2.
Mokhtari A, Ibrahim E, Gloaguen A, Barrot C, Cohen D, Derouin M, et al.
EBioMedicine
. 2025 Feb;
113:105569.
PMID: 39914267
Background: Major depressive disorder (MDD) is a leading cause of disability, with a twofold increase in prevalence in women compared to men. Over the last few years, identifying molecular biomarkers...
3.
de Longprez L, Gaillard M, Decraene C, Perot J, Keime C, Nadkarni N, et al.
Brain
. 2025 Feb;
PMID: 39908340
DCLK3 (Doublecortin-like kinase 3) is a kinase preferentially expressed in neurons. Dclk3 variants are risk factors for psychiatric disorders and brain alterations linked to age-related mild cognitive impairment, suggesting this...
4.
Paiva I, Seguin J, Grgurina I, Singh A, Cosquer B, Plassard D, et al.
Neurobiol Dis
. 2024 May;
198:106538.
PMID: 38789057
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's disease, with epigenome alterations as a contributing factor. Here, we compared transcriptomic/epigenomic changes in the hippocampus, modified...
5.
Falconnier C, Caparros-Roissard A, Decraene C, Lutz P
Mol Psychiatry
. 2023 Sep;
28(11):4568-4584.
PMID: 37723284
In the past two decades, over-prescription of opioids for pain management has driven a steep increase in opioid use disorder (OUD) and death by overdose, exerting a dramatic toll on...
6.
Tzeplaeff L, Seguin J, Le Gras S, Megat S, Cosquer B, Plassard D, et al.
Prog Neurobiol
. 2023 Jun;
227:102483.
PMID: 37327984
Cytoplasmic mislocalization of the nuclear Fused in Sarcoma (FUS) protein is associated to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Cytoplasmic FUS accumulation is recapitulated in the frontal cortex...
7.
Alcala-Vida R, Lotz C, Brule B, Seguin J, Decraene C, Awada A, et al.
Prog Neurobiol
. 2022 Sep;
219:102363.
PMID: 36179935
Molecular mechanisms underlying cognitive deficits in Huntington's disease (HD), a striatal neurodegenerative disorder, are unknown. Here, we generated ChIPseq, 4Cseq and RNAseq data on striatal tissue of HD and control...
8.
Houy S, Streit L, Drissa I, Rame M, Decraene C, Moog S, et al.
Cancer Lett
. 2022 Jun;
543:215765.
PMID: 35680072
Neuroendocrine tumors constitute a heterogeneous group of tumors arising from hormone-secreting cells and are generally associated with a dysfunction of secretion. Pheochromocytoma (Pheo) is a neuroendocrine tumor that develops from...
9.
Bidard F, Kiavue N, Ychou M, Cabel L, Stern M, Madic J, et al.
Cells
. 2019 May;
8(6).
PMID: 31142037
The management of patients with colorectal cancer (CRC) and potentially resectable liver metastases (LM) requires quick assessment of mutational status and of response to pre-operative systemic therapy. In a prospective...
10.
Cabel L, Decraene C, Bieche I, Pierga J, Bennamoun M, Fuks D, et al.
Cancers (Basel)
. 2019 Mar;
11(3).
PMID: 30901876
This study was designed to monitor circulating tumor DNA (ctDNA) levels during perioperative chemotherapy in patients with non-metastatic gastric adenocarcinoma. Plasma samples were prospectively collected in patients undergoing perioperative chemotherapy...