Marc-Henri Stern
Overview
Explore the profile of Marc-Henri Stern including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
5278
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0
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Recent Articles
1.
Cyrta J, Masliah-Planchon J, Hoare O, Brillet R, Andrianteranagna M, Sohier P, et al.
J Pathol
. 2025 Jan;
265(3):357-371.
PMID: 39853675
Rhabdoid tumours (RT) are an aggressive malignancy affecting <2-year-old infants, characterised by biallelic loss-of-function alterations in SWI/SNF-related BAF chromatin remodelling complex subunit B1 (SMARCB1) in nearly all cases. Germline SMARCB1...
2.
Michel M, Heidary M, Mechri A, Da Silva K, Gorse M, Dixon V, et al.
Clin Cancer Res
. 2024 Dec;
PMID: 39620930
Purpose: The detection of circulating tumor DNA, which allows non-invasive tumor molecular profiling and disease follow-up, promises optimal and individualized management of patients with cancer. However, detecting small fractions of...
3.
Silveira A, Houy A, Ganier O, Ozemek B, Vanhuele S, Vincent-Salomon A, et al.
Nat Commun
. 2024 Nov;
15(1):9864.
PMID: 39543136
Transition of cytosine to thymine in CpG dinucleotides is the most frequent type of mutation in cancer. This increased mutability is commonly attributed to the spontaneous deamination of 5-methylcytosine (5mC),...
4.
Mariani P, Pierron G, Ait Rais K, Bouhadiba T, Rodrigues M, Malaise D, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39410027
Surgical treatment of liver metastases of uveal melanoma (LMUM) could be proposed for selected patients. This retrospective study examined the prognostic significance of the genetic profiles of liver metastases after...
5.
Rodrigues M, Ramtohul T, Rampanou A, Sandoval J, Houy A, Servois V, et al.
Nat Commun
. 2024 Oct;
15(1):8851.
PMID: 39402032
Tebentafusp, a bispecific immune therapy, is the only drug that demonstrated an overall survival benefit in patients with metastatic uveal melanoma (MUM). Circulating tumor DNA (ctDNA) has emerged as a...
6.
Protein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status
Gelmi M, de Ru A, Van Veelen P, Tjokrodirijo R, Stern M, Houy A, et al.
Invest Ophthalmol Vis Sci
. 2024 Jul;
65(8):37.
PMID: 39042403
Purpose: Cell lines are being used in preclinical uveal melanoma (UM) research. Because not all cell lines harbor typical GNAQ or GNA11 hotspot mutations, we aimed at better classifying them...
7.
Le Saux O, Ardin M, Berthet J, Barrin S, Bourhis M, Cinier J, et al.
Nat Commun
. 2024 Jul;
15(1):5932.
PMID: 39013886
PD-1/PD-L1 blockade has so far shown limited survival benefit for high-grade ovarian carcinomas. By using paired samples from the NeoPembrOv randomized phase II trial (NCT03275506), for which primary outcomes are...
8.
Rombaut D, Lefevre C, Rached T, Bondu S, Letessier A, Mangione R, et al.
Nat Commun
. 2024 Apr;
15(1):3016.
PMID: 38589367
Myelodysplastic syndromes (MDS) with mutated SF3B1 gene present features including a favourable outcome distinct from MDS with mutations in other splicing factor genes SRSF2 or U2AF1. Molecular bases of these...
9.
Lucibello F, Lalanne A, Le Gac A, Soumare A, Aflaki S, Cyrta J, et al.
J Exp Med
. 2024 Apr;
221(6).
PMID: 38563818
Uveal melanoma (UM) is the most common cancer of the eye. The loss of chromosome 3 (M3) is associated with a high risk of metastases. M3 tumors are more infiltrated...
10.
Schwartz M, Ibadioune S, Vacher S, Villy M, Trabelsi-Grati O, Le Gall J, et al.
Breast
. 2023 Dec;
73:103620.
PMID: 38096711
Breast cancers (BC) are rare in men and are often caused by constitutional predisposing factors. In women, mosaic BRCA1 promoter methylations (MBPM) are frequent events, detected in 4-8% of healthy...