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Brigitte Cosquer

Explore the profile of Brigitte Cosquer including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 752
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Recent Articles
1.
Brule B, Alcala-Vida R, Penaud N, Scuto J, Mounier C, Seguin J, et al.
Nat Commun . 2025 Feb; 16(1):1550. PMID: 39934111
Loss of epigenetic information during physiological aging compromises cellular identity, leading to de-repression of developmental genes. Here, we assessed the epigenomic landscape of vulnerable neurons in two reference mouse models...
2.
Cassel J, Panzer E, Guimaraes-Olmo I, Cosquer B, Pereira de Vasconcelos A, Stephan A
Brain Struct Funct . 2025 Jan; 230(1):26. PMID: 39760747
This mini-review explores sexual dimorphism in the ventral midline thalamus, focusing on the reuniens nucleus and its role in behavioral functions. Traditionally linked to tasks such as working memory, cognitive...
3.
Cassel J, Panzer E, Guimaraes-Olmo I, Cosquer B, Pereira de Vasconcelos A, Stephan A
Neurosci Biobehav Rev . 2024 Oct; 167:105932. PMID: 39454977
The ventral midline thalamus, including the reuniens and rhomboid (ReRh) nuclei, connects bidirectionally with the medial prefrontal cortex (mPFC) and hippocampus (Hip), both essential for memory processes. This review compiles...
4.
Schueller E, Grgurina I, Cosquer B, Panzer E, Penaud N, Pereira de Vasconcelos A, et al.
Neurobiol Dis . 2024 Sep; 201:106676. PMID: 39307398
Background: Dementia with Lewy bodies (DLB) is the second most common age-related neurocognitive pathology after Alzheimer's disease. Animal models characterizing this disease are lacking and their development would ameliorate both...
5.
Paiva I, Seguin J, Grgurina I, Singh A, Cosquer B, Plassard D, et al.
Neurobiol Dis . 2024 May; 198:106538. PMID: 38789057
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's disease, with epigenome alterations as a contributing factor. Here, we compared transcriptomic/epigenomic changes in the hippocampus, modified...
6.
Panzer E, Boch L, Cosquer B, Grgurina I, Boutillier A, Pereira de Vasconcelos A, et al.
J Neurosci Methods . 2024 Feb; 405:110080. PMID: 38369027
Background: The thalamic reuniens (Re) and rhomboid (Rh) nuclei are bidirectionally connected with the medial prefrontal cortex (mPFC) and the hippocampus (Hip). Fiber-sparing N-methyl-D-aspartate lesions of the ReRh disrupt cognitive...
7.
Tzeplaeff L, Seguin J, Le Gras S, Megat S, Cosquer B, Plassard D, et al.
Prog Neurobiol . 2023 Jun; 227:102483. PMID: 37327984
Cytoplasmic mislocalization of the nuclear Fused in Sarcoma (FUS) protein is associated to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Cytoplasmic FUS accumulation is recapitulated in the frontal cortex...
8.
Alcala-Vida R, Lotz C, Brule B, Seguin J, Decraene C, Awada A, et al.
Prog Neurobiol . 2022 Sep; 219:102363. PMID: 36179935
Molecular mechanisms underlying cognitive deficits in Huntington's disease (HD), a striatal neurodegenerative disorder, are unknown. Here, we generated ChIPseq, 4Cseq and RNAseq data on striatal tissue of HD and control...
9.
Boch L, Morvan T, Neige T, Kobakhidze N, Panzer E, Cosquer B, et al.
Behav Brain Res . 2022 Jun; 432:113979. PMID: 35760217
Working memory (WM) is a function operating in three successive phases: encoding (sample trial), holding (delay), and retrieval (test trial) of information. Studies point to a possible implication of the...
10.
Morvan T, Boch L, Mikhina E, Cosquer B, Stephan A, Pereira de Vasconcelos A, et al.
Behav Brain Res . 2021 Nov; 418:113670. PMID: 34798168
The reuniens (Re) and rhomboid (Rh) nuclei of the ventral midline thalamus are bi-directionally connected with the hippocampus and the medial prefrontal cortex. They participate in a variety of cognitive...