Celine Boiteux
Overview
Explore the profile of Celine Boiteux including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
307
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0
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Recent Articles
1.
Boiteux C, Posson D, Allen T, Nimigean C
Proc Natl Acad Sci U S A
. 2020 Nov;
117(47):29968-29978.
PMID: 33154158
Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated channels, such...
2.
Lynagh T, Flood E, Boiteux C, Sheikh Z, Allen T, Pless S
J Gen Physiol
. 2020 Jan;
152(2).
PMID: 31952079
Trimeric acid-sensing ion channels (ASICs) contribute to neuronal signaling by converting extracellular acidification into excitatory sodium currents. Previous work with homomeric ASIC1a implicates conserved leucine (L7') and consecutive glycine-alanine-serine (GAS...
3.
Flood E, Boiteux C, Lev B, Vorobyov I, Allen T
Chem Rev
. 2019 Jun;
119(13):7737-7832.
PMID: 31246417
Membrane ion channels are the fundamental electrical components in the nervous system. Recent developments in X-ray crystallography and cryo-EM microscopy have revealed what these proteins look like in atomic detail...
4.
Flood E, Boiteux C, Allen T
PLoS Comput Biol
. 2018 Sep;
14(9):e1006398.
PMID: 30208027
Bacterial and human voltage-gated sodium channels (Navs) exhibit similar cation selectivity, despite their distinct EEEE and DEKA selectivity filter signature sequences. Recent high-resolution structures for bacterial Navs have allowed us...
5.
Boiteux C, Flood E, Allen T
Neurosci Lett
. 2018 May;
700:3-8.
PMID: 29807068
Voltage-gated sodium channels are the molecular components of electrical signaling in the body, yet the molecular origins of Na-selective transport remain obscured by diverse protein chemistries within this family of...
6.
Lynagh T, Flood E, Boiteux C, Wulf M, Komnatnyy V, Colding J, et al.
Elife
. 2017 May;
6.
PMID: 28498103
Increased extracellular proton concentrations during neurotransmission are converted to excitatory sodium influx by acid-sensing ion channels (ASICs). 10-fold sodium/potassium selectivity in ASICs has long been attributed to a central constriction...
7.
Boiteux C, Vorobyov I, French R, French C, Yarov-Yarovoy V, Allen T
Proc Natl Acad Sci U S A
. 2014 Aug;
111(36):13057-62.
PMID: 25136136
Voltage-gated sodium (Nav) channels are important targets in the treatment of a range of pathologies. Bacterial channels, for which crystal structures have been solved, exhibit modulation by local anesthetic and...
8.
Boiteux C, Vorobyov I, Allen T
Proc Natl Acad Sci U S A
. 2014 Feb;
111(9):3454-9.
PMID: 24550503
Voltage-gated Na(+) channels play an essential role in electrical signaling in the nervous system and are key pharmacological targets for a range of disorders. The recent solution of X-ray structures...
9.
Roy S, Boiteux C, Alijevic O, Liang C, Berneche S, Kellenberger S
FASEB J
. 2013 Sep;
27(12):5034-45.
PMID: 24018065
Epithelial Na(+) channel (ENaC)/degenerin family members are involved in mechanosensation, blood pressure control, pain sensation, and the expression of fear. Several of these channel types display a form of desensitization...
10.
Silvan U, Boiteux C, Sutterlin R, Schroeder U, Mannherz H, Jockusch B, et al.
J Struct Biol
. 2011 Oct;
177(1):70-80.
PMID: 21970948
The dynamic rearrangement of the actin cytoskeleton plays a key role in several cellular processes such as cell motility, endocytosis, RNA processing and chromatin organization. However, the supramolecular actin structures...