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Catherine Pan

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Articles 42
Citations 1941
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Recent Articles
1.
Zhang A, Gao Q, Tian C, Chen W, Pan C, Wang L, et al.
Lab Invest . 2024 Oct; 104(12):102151. PMID: 39419350
Non-small cell lung cancer (NSCLC) remains a leading cause of global mortality, with current screening and diagnostic methods often lacking in sensitivity and specificity. In our endeavor to develop precise,...
2.
Tian C, Stewart T, Hong Z, Guo Z, Aro P, Soltys D, et al.
Alzheimers Dement . 2022 Jul; 19(3):909-923. PMID: 35779041
Introduction: Objective and accessible markers for Alzheimer's disease (AD) and other dementias are critically needed. Methods: We identified NMDAR2A, a protein related to synaptic function, as a novel marker of...
3.
Hong Z, Tian C, Stewart T, Aro P, Soltys D, Bercow M, et al.
Neurology . 2021 May; 96(18):e2332-e2345. PMID: 34032594
Objective: To develop a reliable and fast assay to quantify the α-synuclein (α-syn)-containing extracellular vesicles (EVs) in CSF and to assess their diagnostic potential for Parkinson disease (PD). Methods: A...
4.
Parada C, Osbun J, Busald T, Karasozen Y, Kaur S, Shi M, et al.
Clin Cancer Res . 2019 Oct; 26(1):193-205. PMID: 31615938
Purpose: Most World Health Organization (WHO) grade I meningiomas carry a favorable prognosis. Some become clinically aggressive with recurrence, invasion, and resistance to conventional therapies (grade 1.5; recurrent/progressive WHO grade...
5.
Tian C, Liu G, Gao L, Soltys D, Pan C, Stewart T, et al.
Transl Neurodegener . 2019 May; 8:15. PMID: 31123587
Background: Erythrocytes are a major source of peripheral α-synuclein (α-Syn). The goal of the current investigation is to evaluate erythrocytic total, oligomeric/aggregated, and phosphorylated α-Syn species as biomarkers of Parkinson's...
6.
Parada C, Osbun J, Kaur S, Yakkioui Y, Shi M, Pan C, et al.
Sci Rep . 2018 Feb; 8(1):2098. PMID: 29391485
There is a need to better understand meningioma oncogenesis for biomarker discovery and development of targeted therapies. Histological or genetic criteria do not accurately predict aggressiveness. Post-translational studies in meningioma...
7.
Yang L, Stewart T, Shi M, Pottiez G, Dator R, Wu R, et al.
Proteomics Clin Appl . 2017 Mar; 11(7-8). PMID: 28319654
Aim: The alpha-synuclein (α-syn) level in human cerebrospinal fluid (CSF), as measured by immunoassays, is promising as a Parkinson's disease (PD) biomarker. However, the levels of total α-syn are inconsistent...
8.
Li G, Xiong K, Korff A, Pan C, Quinn J, Galasko D, et al.
J Alzheimers Dis . 2015 Sep; 47(4):883-7. PMID: 26401768
Clinically diagnosed Alzheimer's disease (AD) is pathologically heterogeneous. In this multicenter cohort of 215 clinically diagnosed AD patients and 249 controls, E-selectin and vascular cell adhesion molecule 1 (VACM-1) were...
9.
Pan C, Korff A, Galasko D, Ginghina C, Peskind E, Li G, et al.
J Alzheimers Dis . 2015 Jan; 45(3):709-19. PMID: 25613100
Background: Meso Scale Discovery (MSD) recently established electrochemiluminescence-based assays to measure cerebrospinal fluid (CSF) levels of total tau (t-tau) and amyloid-β 1-42 peptide (Aβ42) that can aid in the diagnosis...
10.
Shi M, Movius J, Dator R, Aro P, Zhao Y, Pan C, et al.
Mol Cell Proteomics . 2015 Jan; 14(3):544-55. PMID: 25556233
Finding robust biomarkers for Parkinson disease (PD) is currently hampered by inherent technical limitations associated with imaging or antibody-based protein assays. To circumvent the challenges, we adapted a staged pipeline,...