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Catherine Pan

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Articles 42
Citations 1941
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Recent Articles
11.
Pan C, Zhou Y, Dator R, Ginghina C, Zhao Y, Movius J, et al.
J Proteome Res . 2014 May; 13(11):4535-45. PMID: 24853996
Despite extensive research, an unmet need remains for protein biomarkers of Parkinson's disease (PD) in peripheral body fluids, especially blood, which is easily accessible clinically. The discovery of such biomarkers...
12.
Devic I, Shi M, Schubert M, Lloid M, Izutsu K, Pan C, et al.
Biol Blood Marrow Transplant . 2014 Apr; 20(7):1048-55. PMID: 24704387
Chronic graft-versus-host disease (cGVHD) is an immune-mediated disorder and is the major long-term complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). The oral mucosa, including the salivary glands, is affected...
13.
Lin X, Cook T, Zabetian C, Leverenz J, Peskind E, Hu S, et al.
Sci Rep . 2012 Dec; 2:954. PMID: 23233873
DJ-1 is a multifunctional protein that plays an important role in oxidative stress, cell death, and synucleinopathies, including Parkinson disease. Previous studies have demonstrated that total DJ-1 levels decrease in...
14.
Maccecchini M, Young Chang M, Pan C, John V, Zetterberg H, Greig N
J Neurol Neurosurg Psychiatry . 2012 Jul; 83(9):894-902. PMID: 22791904
Aim: A first in human study to evaluate tolerability and pharmacokinetics followed by an early proof of mechanism (POM) study to determine whether the small orally, available molecule, Posiphen tartrate...
15.
Wang Y, Shi M, Chung K, Zabetian C, Leverenz J, Berg D, et al.
Sci Transl Med . 2012 Feb; 4(121):121ra20. PMID: 22344688
Phosphorylated α-synuclein (PS-129), a protein implicated in the pathogenesis of Parkinson's disease (PD), was identified by mass spectrometry in human cerebrospinal fluid (CSF). A highly sensitive and specific assay was...
16.
Shi M, Sui Y, Peskind E, Li G, Hwang H, Devic I, et al.
J Alzheimers Dis . 2011 Aug; 27(2):299-305. PMID: 21841250
Phosphorylation of tau protein is a critical event in the pathogenesis of Alzheimer's disease (AD). Increased phosphorylated tau and total tau levels, combined with reduced concentrations of amyloid-β 1-42 (Aβ42)...
17.
Devic I, Hwang H, Edgar J, Izutsu K, Presland R, Pan C, et al.
Brain . 2011 Feb; 134(Pt 7):e178. PMID: 21349902
No abstract available.
18.
Kitsou E, Pan S, Zhang J, Shi M, Zabeti A, Dickson D, et al.
Proteomics Clin Appl . 2010 Dec; 2(5):776-82. PMID: 21136874
Characterization of the human brain proteome is a critical area of research. While examination of the human cortex has provided some insight, very little is known about the proteome of...
19.
Rostomily R, Born D, Beyer R, Jin J, Alvord Jr E, Mikheev A, et al.
J Proteome Res . 2010 Mar; 9(5):2610-8. PMID: 20337498
Approximately 50-80% of oligodendrogliomas demonstrate a combined loss of chromosome 1p and 19q. Chromosome 1p/19q deletion, appearing early in tumorigenesis, is associated with improved clinical outcomes, including response to chemotherapy...
20.
Hong Z, Shi M, Chung K, Quinn J, Peskind E, Galasko D, et al.
Brain . 2010 Feb; 133(Pt 3):713-26. PMID: 20157014
Biomarkers are urgently needed for the diagnosis and monitoring of disease progression in Parkinson's disease. Both DJ-1 and alpha-synuclein, two proteins critically involved in Parkinson's disease pathogenesis, have been tested...