Carolyn McGrail
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Explore the profile of Carolyn McGrail including associated specialties, affiliations and a list of published articles.
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9
Citations
26
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Recent Articles
1.
Melton R, Jimenez S, Elison W, Tucciarone L, Howell A, Wang G, et al.
bioRxiv
. 2025 Mar;
PMID: 40027657
Cell type-specific regulatory programs that drive type 1 diabetes (T1D) in the pancreas are poorly understood. Here we performed single nucleus multiomics and spatial transcriptomics in up to 32 non-diabetic...
2.
McGrail C, Chiou J, Elgamal R, Egamal R, Luckett A, Oram R, et al.
Diabetes Care
. 2024 Dec;
48(2):202-211.
PMID: 39626097
Objective: More than 10% of patients with type 1 diabetes (T1D) do not have high-risk HLA-DR3 or -DR4 haplotypes with distinct clinical features, such as later onset and reduced insulin...
3.
McGrail C, Sears T, Kudtarkar P, Carter H, Gaulton K
medRxiv
. 2024 Aug;
PMID: 39132494
Type 1 diabetes (T1D) has a large genetic component, and expanded genetic studies of T1D can lead to novel biological and therapeutic discovery and improved risk prediction. In this study,...
4.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, et al.
Nat Med
. 2024 May;
30(7):2091.
PMID: 38760590
No abstract available.
5.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, et al.
Nat Med
. 2024 Mar;
30(4):1065-1074.
PMID: 38443691
Type 2 diabetes (T2D) is a multifactorial disease with substantial genetic risk, for which the underlying biological mechanisms are not fully understood. In this study, we identified multi-ancestry T2D genetic...
6.
McGrail C, Chiou J, Elgamal R, Luckett A, Oram R, Benaglio P, et al.
medRxiv
. 2023 Nov;
PMID: 37986756
Over 10% of type 1 diabetes (T1D) cases do not have high-risk HLA-DR3 or DR4 haplotypes with distinct clinical features such as later onset and reduced insulin dependence. To identify...
7.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Mandla R, et al.
Res Sq
. 2023 Oct;
PMID: 37886436
We identified genetic subtypes of type 2 diabetes (T2D) by analyzing genetic data from diverse groups, including non-European populations. We implemented soft clustering with 650 T2D-associated genetic variants, capturing known...
8.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Mandla R, et al.
medRxiv
. 2023 Oct;
PMID: 37808749
We identified genetic subtypes of type 2 diabetes (T2D) by analyzing genetic data from diverse groups, including non-European populations. We implemented soft clustering with 650 T2D-associated genetic variants, capturing known...
9.
Wortham M, Liu F, Harrington A, Fleischman J, Wallace M, Mulas F, et al.
J Clin Invest
. 2023 Feb;
133(8).
PMID: 36821378
Adaptation of the islet β cell insulin-secretory response to changing insulin demand is critical for blood glucose homeostasis, yet the mechanisms underlying this adaptation are unknown. Here, we have shown...
10.
McGrail C, Urban J, Church B, Corser W
Spartan Med Res J
. 2021 Mar;
1(1):5097.
PMID: 33655101
Context: It is now increasingly recognized that physicians should be engaged in quality improvement/patient safety (QIPS) activities to make their patient care systems perform more reliably and safely. In order...