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Alice Williamson

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Articles 14
Citations 138
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Recent Articles
1.
Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs B, Samuel M, et al.
Nat Med . 2024 Nov; 31(1):323-331. PMID: 39592779
South Asians develop type 2 diabetes (T2D) early in life and often with normal body mass index (BMI). However, reasons for this are poorly understood because genetic research is largely...
2.
Alwan H, Luan J, Williamson A, Carrasco-Zanini J, Stewart I, Wareham N, et al.
EBioMedicine . 2024 Aug; 107:105306. PMID: 39191175
Background: Variation in thyroid function parameters within the normal range has been observationally associated with adverse health outcomes. Whether those associations reflect causal effects is largely unknown. Methods: We systematically...
3.
Williamson A, Fatumo S
Science . 2024 Jul; 385(6706):255-256. PMID: 39024460
Genomic data from different populations will improve understanding of complex diseases.
4.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, et al.
Nat Med . 2024 May; 30(7):2091. PMID: 38760590
No abstract available.
5.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, et al.
Nat Med . 2024 Mar; 30(4):1065-1074. PMID: 38443691
Type 2 diabetes (T2D) is a multifactorial disease with substantial genetic risk, for which the underlying biological mechanisms are not fully understood. In this study, we identified multi-ancestry T2D genetic...
6.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature . 2024 Feb; 627(8003):347-357. PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
7.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Mandla R, et al.
Res Sq . 2023 Oct; PMID: 37886436
We identified genetic subtypes of type 2 diabetes (T2D) by analyzing genetic data from diverse groups, including non-European populations. We implemented soft clustering with 650 T2D-associated genetic variants, capturing known...
8.
Smith K, Deutsch A, McGrail C, Kim H, Hsu S, Mandla R, et al.
medRxiv . 2023 Oct; PMID: 37808749
We identified genetic subtypes of type 2 diabetes (T2D) by analyzing genetic data from diverse groups, including non-European populations. We implemented soft clustering with 650 T2D-associated genetic variants, capturing known...
9.
Duckett K, Williamson A, Kincaid J, Rainbow K, Corbin L, Martin H, et al.
J Clin Endocrinol Metab . 2023 Jun; 108(12):e1580-e1587. PMID: 37339320
Context: The melanocortin 3 receptor (MC3R) has recently emerged as a critical regulator of pubertal timing, linear growth, and the acquisition of lean mass in humans and mice. In population-based...
10.
Williamson A, Norris D, Yin X, Broadaway K, Moxley A, Vadlamudi S, et al.
Nat Genet . 2023 Jun; 55(6):973-983. PMID: 37291194
Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on insulin resistance in the fasting state, where hepatic insulin action dominates. Here...